| Literature DB >> 9717214 |
Abstract
Small, asexual populations are expected to accumulate deleterious substitutions and deletions in an irreversible manner, which in the long-term will lead to mutational meltdown and genome decay. Here, we discuss the influence of such reductive processes on the evolution of genomes that replicate within the domain of a host genome.Mesh:
Year: 1998 PMID: 9717214 DOI: 10.1016/s0966-842x(98)01312-2
Source DB: PubMed Journal: Trends Microbiol ISSN: 0966-842X Impact factor: 17.079