Extensive skin candidosis in an adult: effective treatment with itraconazole.

A 34-year-old man with 6 years' untreated erythematous scaling of the skin was diagnosed as having extensive skin candidosis. Oral itraconazole was administered for 4 weeks (400 mg day-1 for the first 3 weeks and 200 mg day-1 for the last week). At the end of the 4-week treatment period, the rash was completely cleared from all skin sites, and Candida albicans was absent in culture tests on tissue samples. No adverse events were reported by the patient, and laboratory analysis revealed no abnormalities in the liver, kidney and haematological systems. Oral itraconazole is therefore an effective treatment for extensive skin candidosis.