| Literature DB >> 9714851 |
W Shi1, H S Wang, Z Pan, R S Wymore, I S Cohen, D McKinnon, J E Dixon.
Abstract
1. Three new members of the EAG potassium channel gene family were identified in rat and the complete coding sequence of one of these genes (elk1) was determined by cDNA cloning. 2. The elk1 gene, when expressed in Xenopus oocytes, encodes a slowly activating and slowly deactivating potassium channel. 3. The elk1 gene is expressed in sympathetic ganglia and is also expressed in sciatic nerve. 4. Six of the seven known EAG genes were found to be expressed in rat sympathetic ganglia, suggesting an important functional role for these channels in the sympathetic nervous system.Entities:
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Year: 1998 PMID: 9714851 PMCID: PMC2231163 DOI: 10.1111/j.1469-7793.1998.675bg.x
Source DB: PubMed Journal: J Physiol ISSN: 0022-3751 Impact factor: 5.182