Literature DB >> 9714738

Molecular cloning and expression of human chondroitin 6-sulfotransferase.

M Fukuta1, Y Kobayashi, K Uchimura, K Kimata, O Habuchi.   

Abstract

Using cDNA of chick chondroitin 6-sulfotransferase (C6ST), human C6ST cDNA has been isolated. The amino acid sequence of human C6ST displayed 74% identity to chick C6ST. The major difference in amino acid sequence between chick C6ST and human C6ST was the presence of a unique hydrophilic domain in human C6ST. A 7.8-kb message of C6ST was expressed ubiquitously in various human adult tissues, indicating a rather diverse function of C6ST.

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Year:  1998        PMID: 9714738     DOI: 10.1016/s0167-4781(98)00089-x

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  17 in total

1.  Baculovirus envelope protein ODV-E66 is a novel chondroitinase with distinct substrate specificity.

Authors:  Nobuo Sugiura; Yuka Setoyama; Mie Chiba; Koji Kimata; Hideto Watanabe
Journal:  J Biol Chem       Date:  2011-06-29       Impact factor: 5.157

Review 2.  Human genetic disorders caused by mutations in genes encoding biosynthetic enzymes for sulfated glycosaminoglycans.

Authors:  Shuji Mizumoto; Shiro Ikegawa; Kazuyuki Sugahara
Journal:  J Biol Chem       Date:  2013-03-01       Impact factor: 5.157

3.  Chondroitin 4-sulphotransferase-1 and chondroitin 6-sulphotransferase-1 are affected differently by uronic acid residues neighbouring the acceptor GalNAc residues.

Authors:  Takayoshi Yamada; Shiori Ohtake; Makoto Sato; Osami Habuchi
Journal:  Biochem J       Date:  2004-12-15       Impact factor: 3.857

4.  A versatile polyacrylamide gel electrophoresis based sulfotransferase assay.

Authors:  Zhengliang L Wu; Cheryl M Ethen; Sara Larson; Brittany Prather; Weiping Jiang
Journal:  BMC Biotechnol       Date:  2010-02-10       Impact factor: 2.563

5.  Gene silencing of EXTL2 and EXTL3 as a substrate deprivation therapy for heparan sulphate storing mucopolysaccharidoses.

Authors:  Xenia Kaidonis; Wan Chin Liaw; Ainslie Derrick Roberts; Marleesa Ly; Donald Anson; Sharon Byers
Journal:  Eur J Hum Genet       Date:  2009-08-19       Impact factor: 4.246

6.  Construction of a chondroitin sulfate library with defined structures and analysis of molecular interactions.

Authors:  Nobuo Sugiura; Tatsumasa Shioiri; Mie Chiba; Takashi Sato; Hisashi Narimatsu; Koji Kimata; Hideto Watanabe
Journal:  J Biol Chem       Date:  2012-11-05       Impact factor: 5.157

7.  Loss of chondroitin 6-O-sulfotransferase-1 function results in severe human chondrodysplasia with progressive spinal involvement.

Authors:  Holger Thiele; Masahiro Sakano; Hiroshi Kitagawa; Kazuyuki Sugahara; Anna Rajab; Wolfgang Höhne; Heide Ritter; Gundula Leschik; Peter Nürnberg; Stefan Mundlos
Journal:  Proc Natl Acad Sci U S A       Date:  2004-06-23       Impact factor: 11.205

8.  Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11 gene expression in forming surface P-selectin ligands in aggressive breast cancer cells.

Authors:  Craig A Cooney; Fariba Jousheghany; Aiwei Yao-Borengasser; Bounleut Phanavanh; Tina Gomes; Ann Marie Kieber-Emmons; Eric R Siegel; Larry J Suva; Soldano Ferrone; Thomas Kieber-Emmons; Behjatolah Monzavi-Karbassi
Journal:  Breast Cancer Res       Date:  2011-06-09       Impact factor: 6.466

9.  Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectin.

Authors:  A Bistrup; S Bhakta; J K Lee; Y Y Belov; M D Gunn; F R Zuo; C C Huang; R Kannagi; S D Rosen; S Hemmerich
Journal:  J Cell Biol       Date:  1999-05-17       Impact factor: 10.539

10.  Chondroitin / dermatan sulfate modification enzymes in zebrafish development.

Authors:  Judith Habicher; Tatjana Haitina; Inger Eriksson; Katarina Holmborn; Tabea Dierker; Per E Ahlberg; Johan Ledin
Journal:  PLoS One       Date:  2015-03-20       Impact factor: 3.240

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