Literature DB >> 9713596

A non-isotopic method for the detection of telomerase activity in tumour tissues: TRAP-silver staining assay.

J M Wen1, L B Sun, M Zhang, M H Zheng.   

Abstract

Telomerase activity has been observed in a high proportion of specimens from a wide variety of human malignant tumours, but not in non-neoplastic tissues. Measurement of telomerase activity is a possible diagnostic maker for malignant tumours. A non-isotopic telomeric repeat amplification protocol (TRAP) silver staining method for the detection of telomerase activity in human bone tumour tissues is described. The TRAP-silver staining method was quick, safe, and effective, and can be used as a routine diagnostic method for the detection of telomerase activity in bone tumours.

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Year:  1998        PMID： 9713596      PMCID： PMC395620          DOI： 10.1136/mp.51.2.110

Source DB:  PubMed          Journal:  Mol Pathol        ISSN： 1366-8714


  11 in total

1.  Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients.

Authors:  J Califano; S A Ahrendt; G Meininger; W H Westra; W M Koch; D Sidransky
Journal:  Cancer Res       Date:  1996-12-15       Impact factor: 12.701

2.  Telomerase activity in reactive and neoplastic lymphoid tissues: infrequent detection of activity in Hodgkin's disease.

Authors:  P Brousset; T al Saati; N Chaouche; R C Zenou; D Schlaifer; S Chittal; G Delsol
Journal:  Blood       Date:  1997-01-01       Impact factor: 22.113

3.  Telomerase activity and telomere length in hepatocellular carcinoma and chronic liver disease.

Authors:  H Kojima; O Yokosuka; F Imazeki; H Saisho; M Omata
Journal:  Gastroenterology       Date:  1997-02       Impact factor: 22.682

4.  Telomerase activity in primary prostate cancer.

Authors:  Y Lin; H Uemura; K Fujinami; M Hosaka; M Harada; Y Kubota
Journal:  J Urol       Date:  1997-03       Impact factor: 7.450

5.  Telomerase activity in human ovarian carcinoma.

Authors:  C M Counter; H W Hirte; S Bacchetti; C B Harley
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-12       Impact factor: 11.205

6.  Correlating telomerase activity levels with human neuroblastoma outcomes.

Authors:  E Hiyama; K Hiyama; T Yokoyama; Y Matsuura; M A Piatyszek; J W Shay
Journal:  Nat Med       Date:  1995-03       Impact factor: 53.440

7.  Specific association of human telomerase activity with immortal cells and cancer.

Authors:  N W Kim; M A Piatyszek; K R Prowse; C B Harley; M D West; P L Ho; G M Coviello; W E Wright; S L Weinrich; J W Shay
Journal:  Science       Date:  1994-12-23       Impact factor: 47.728

8.  Telomerase activity in small-cell and non-small-cell lung cancers.

Authors:  K Hiyama; E Hiyama; S Ishioka; M Yamakido; K Inai; A F Gazdar; M A Piatyszek; J W Shay
Journal:  J Natl Cancer Inst       Date:  1995-06-21       Impact factor: 13.506

9.  Telomerase activity in human breast cancer and benign breast lesions: diagnostic applications in clinical specimens, including fine needle aspirates.

Authors:  T Sugino; K Yoshida; J Bolodeoku; H Tahara; I Buley; S Manek; C Wells; S Goodison; T Ide; T Suzuki; E Tahara; D Tarin
Journal:  Int J Cancer       Date:  1996-08-22       Impact factor: 7.396

10.  Telomerase activity associated with acquisition of malignancy in human colorectal cancer.

Authors:  C Chadeneau; K Hay; H W Hirte; S Gallinger; S Bacchetti
Journal:  Cancer Res       Date:  1995-06-15       Impact factor: 12.701
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  5 in total

1.  What We Know about the Molecular Genetics of Central Nervous System (CNS) Tumours in Malaysia.

Authors:  Sarina Sulong; Abdul Aziz Mohamed Yusoff; Norafiza Zainuddin; Jafri Malin Abdullah; Jain George Pannatil; Hasnan Jaafar; Mohd Nizam Isa
Journal:  Malays J Med Sci       Date:  2004-01

2.  Telomere length is short in PCOS and oral contraceptive does not affect the telomerase activity in granulosa cells of patients with PCOS.

Authors:  Ying Li; Bingbing Deng; Nengyong Ouyang; Ping Yuan; Lingyan Zheng; Wenjun Wang
Journal:  J Assist Reprod Genet       Date:  2017-05-06       Impact factor: 3.412

3.  Women with high telomerase activity in luteinised granulosa cells have a higher pregnancy rate during in vitro fertilisation treatment.

Authors:  Hong Chen; Wenjun Wang; Yaqin Mo; Yun Ma; Nengyong Ouyang; Ruiqi Li; Meiqi Mai; Yingming He; M M Abide Bodombossou-Djobo; Dongzi Yang
Journal:  J Assist Reprod Genet       Date:  2011-06-30       Impact factor: 3.412

4.  Phytochemical, acute toxicity and renal protective appraisal of Ajuga parviflora hydromethanolic leaf extract against CCl4 induced renal injury in rats.

Authors:  Samiullah Burki; Zeba Gul Burki; Muhammad Arif Asghar; Imdad Ali; Saba Zafar
Journal:  BMC Complement Med Ther       Date:  2021-07-12

5.  Protective effects of rutin against potassium bromate induced nephrotoxicity in rats.

Authors:  Rahmat Ali Khan; Muhamad Rashid Khan; Sumaira Sahreen
Journal:  BMC Complement Altern Med       Date:  2012-11-01       Impact factor: 3.659
  5 in total

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