Literature DB >> 9713534

Associations between physical examination, laboratory, and radiographic findings and outcome and subsequent racing performance of foals with Rhodococcus equi infection: 115 cases (1984-1992).

D M Ainsworth1, S W Eicker, A E Yeagar, C R Sweeney, L Viel, D Tesarowski, J P Lavoie, A Hoffman, M R Paradis, S M Reed, H N Erb, E Davidow, M Nalevanko.   

Abstract

OBJECTIVE: To determine whether physical examination, laboratory, or radiographic abnormalities in foals with Rhodococcus equi infection were associated with survival, ability to race at least once after recovery, or, for foals that survived and went on to race, subsequent racing performance.
DESIGN: Retrospective study. ANIMALS: 49 Thoroughbreds and 66 Standardbreds admitted to 1 of 6 veterinary teaching hospitals between 1984 and 1992 in which R equi infection was positively diagnosed. PROCEDURE: Results of physical examination, laboratory testing, and thoracic radiography were reviewed. Indices of racing performance were obtained for foals that recovered and eventually raced and compared with values for the US racing population.
RESULTS: 83 (72%) foals survived. Foals that did not survive were more likely to have extreme tachycardia (heart rate > 100 beats/min), be in respiratory distress, and have severe radiographic abnormalities on thoracic radiographs at the time of initial examination than were foals that survived. Clinicopathologic abnormalities were not associated with whether foals did or did not survive. Forty-five of the 83 surviving foals (54%) eventually raced at least once, but none of the factors examined was associated with whether foals went on to race. Racing performance of foals that raced as adults was not significantly different from that of the US racing population. CLINICAL IMPLICATIONS: R equi infection in foals is associated with a decreased chance of racing as an adult; however, foals that eventually go on to race perform comparably to the US racing population.

Entities:  

Mesh:

Year:  1998        PMID: 9713534

Source DB:  PubMed          Journal:  J Am Vet Med Assoc        ISSN: 0003-1488            Impact factor:   1.936


  9 in total

1.  Characterization of the role of the pathogenicity island and vapG in the virulence of the intracellular actinomycete pathogen Rhodococcus equi.

Authors:  Garry B Coulson; Shruti Agarwal; Mary K Hondalus
Journal:  Infect Immun       Date:  2010-05-03       Impact factor: 3.441

2.  Performance of five serological assays for diagnosis of Rhodococcus equi pneumonia in foals.

Authors:  Steeve Giguère; Jorge Hernandez; Jack Gaskin; John F Prescott; Shinji Takai; Corey Miller
Journal:  Clin Diagn Lab Immunol       Date:  2003-03

3.  In vitro susceptibilities of Rhodococcus equi and other common equine pathogens to azithromycin, clarithromycin, and 20 other antimicrobials.

Authors:  Stephanie S Jacks; Steeve Giguère; An Nguyen
Journal:  Antimicrob Agents Chemother       Date:  2003-05       Impact factor: 5.191

4.  Effect of Macrolide and Rifampin Resistance on the Fitness of Rhodococcus equi.

Authors:  Jennifer M Willingham-Lane; Londa J Berghaus; Roy D Berghaus; Kelsey A Hart; Steeve Giguère
Journal:  Appl Environ Microbiol       Date:  2019-03-22       Impact factor: 4.792

Review 5.  Epidemiology and Molecular Basis of Multidrug Resistance in Rhodococcus equi.

Authors:  Sonsiray Álvarez-Narváez; Laura Huber; Steeve Giguère; Kelsey A Hart; Roy D Berghaus; Susan Sanchez; Noah D Cohen
Journal:  Microbiol Mol Biol Rev       Date:  2021-04-14       Impact factor: 11.056

6.  Resistance studies of erythromycin and rifampin for Rhodococcus equi over a 10-year period.

Authors:  T Buckley; E McManamon; S Stanbridge
Journal:  Ir Vet J       Date:  2007-12-01       Impact factor: 2.146

7.  The effectiveness of anti-R. equi hyperimmune plasma against R. equi challenge in thoroughbred Arabian foals of mares vaccinated with R. equi vaccine.

Authors:  Osman Erganis; Zafer Sayin; Hasan Huseyin Hadimli; Asli Sakmanoglu; Yasemin Pinarkara; Ozgur Ozdemir; Mehmet Maden
Journal:  ScientificWorldJournal       Date:  2014-04-03

8.  Randomized, controlled trial comparing Rhodococcus equi and poly-N-acetyl glucosamine hyperimmune plasma to prevent R equi pneumonia in foals.

Authors:  Susanne K Kahn; Colette Cywes-Bentley; Glenn P Blodgett; Nathan M Canaday; Carly E Turner-Garcia; Patricia Flores-Ahlschwede; Laurie L Metcalfe; Mark Nevill; Mariana Vinacur; Patrick J Sutter; Sarah C Meyer; Angela I Bordin; Gerald B Pier; Noah D Cohen
Journal:  J Vet Intern Med       Date:  2021-11-05       Impact factor: 3.333

9.  Identification of genomic loci associated with Rhodococcus equi susceptibility in foals.

Authors:  Cole M McQueen; Ryan Doan; Scott V Dindot; Jessica R Bourquin; Zlatomir Z Zlatev; M Keith Chaffin; Glenn P Blodgett; Ivan Ivanov; Noah D Cohen
Journal:  PLoS One       Date:  2014-06-03       Impact factor: 3.240

  9 in total

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