Literature DB >> 9712820

E and P selectins are not required for resistance to severe murine lyme arthritis.

K P Seiler1, Y Ma, J H Weis, P S Frenette, R O Hynes, D D Wagner, J J Weis.   

Abstract

Borrelia burgdorferi-induced arthritis in mice is characterized by tendonitis, synovitis, and inflammatory-cell infiltrate, predominantly of neutrophils. Because genetic deficiency in E and P selectins results in delayed recruitment of neutrophils to sites of inflammation, mice with this deficiency were tested for their response to infection with B. burgdorferi. E and P selectins were not required for the control of B. burgdorferi numbers, nor did deficiency in E and P selectins result in alteration of arthritis severity.

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Year:  1998        PMID： 9712820      PMCID： PMC108558          DOI： 10.1128/IAI.66.9.4557-4559.1998

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  19 in total

1.  Borrelia burgdorferi upregulates the adhesion molecules E-selectin, P-selectin, ICAM-1 and VCAM-1 on mouse endothelioma cells in vitro.

Authors:  E Böggemeyer; T Stehle; U E Schaible; M Hahne; D Vestweber; M M Simon
Journal:  Cell Adhes Commun       Date:  1994-06

Review 2.  Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm.

Authors:  T A Springer
Journal:  Cell       Date:  1994-01-28       Impact factor: 41.582

Review 3.  Lyme disease.

Authors:  J J Nocton; A C Steere
Journal:  Adv Intern Med       Date:  1995

4.  Distinct characteristics of resistance to Borrelia burgdorferi-induced arthritis in C57BL/6N mice.

Authors:  Y Ma; K P Seiler; E J Eichwald; J H Weis; C Teuscher; J J Weis
Journal:  Infect Immun       Date:  1998-01       Impact factor: 3.441

5.  Lyme borreliosis in selected strains and ages of laboratory mice.

Authors:  S W Barthold; D S Beck; G M Hansen; G A Terwilliger; K D Moody
Journal:  J Infect Dis       Date:  1990-07       Impact factor: 5.226

6.  Borrelia burgdorferi upregulates expression of adhesion molecules on endothelial cells and promotes transendothelial migration of neutrophils in vitro.

Authors:  T J Sellati; M J Burns; M A Ficazzola; M B Furie
Journal:  Infect Immun       Date:  1995-11       Impact factor: 3.441

7.  Heritable susceptibility to severe Borrelia burgdorferi-induced arthritis is dominant and is associated with persistence of large numbers of spirochetes in tissues.

Authors:  L Yang; J H Weis; E Eichwald; C P Kolbert; D H Persing; J J Weis
Journal:  Infect Immun       Date:  1994-02       Impact factor: 3.441

8.  Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins.

Authors:  P S Frenette; T N Mayadas; H Rayburn; R O Hynes; D D Wagner
Journal:  Cell       Date:  1996-02-23       Impact factor: 41.582

9.  Exacerbation of Lyme arthritis in beige mice.

Authors:  S W Barthold; M de Souza
Journal:  J Infect Dis       Date:  1995-09       Impact factor: 5.226

10.  Expression of endothelial cell adhesion molecules in joints and heart during Borrelia burgdorferi infection of mice.

Authors:  U E Schaible; D Vestweber; E G Butcher; T Stehle; M M Simon
Journal:  Cell Adhes Commun       Date:  1994-12
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  1 in total

1.  Treatment of mice with the neutrophil-depleting antibody RB6-8C5 results in early development of experimental lyme arthritis via the recruitment of Gr-1- polymorphonuclear leukocyte-like cells.

Authors:  Charles R Brown; Victoria A Blaho; Christie M Loiacono
Journal:  Infect Immun       Date:  2004-09       Impact factor: 3.441
  1 in total

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