Literature DB >> 9712819

Paclitaxel (Taxol)-induced killing of Leishmania major in murine macrophages.

T M Doherty1, A Sher, S N Vogel.   

Abstract

The antitumor drug paclitaxel (Taxol) has been demonstrated to be a lipopolysaccharide mimetic in murine macrophages. In this study, the capacity of paclitaxel to activate macrophages to become microbicidal for Leishmania major was examined. Paclitaxel and gamma interferon synergized to kill intracellular L. major in Lpsn, but not Lpsd, macrophages by a nitric oxide (NO.)-dependent mechanism.

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Year:  1998        PMID： 9712819      PMCID： PMC108557          DOI： 10.1128/IAI.66.9.4553-4556.1998

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  25 in total

Review 1.  Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.

Authors:  J S Abrams; M G Roncarolo; H Yssel; U Andersson; G J Gleich; J E Silver
Journal:  Immunol Rev       Date:  1992-06       Impact factor: 12.988

2.  IL-10 synergizes with IL-4 and transforming growth factor-beta to inhibit macrophage cytotoxic activity.

Authors:  I P Oswald; R T Gazzinelli; A Sher; S L James
Journal:  J Immunol       Date:  1992-06-01       Impact factor: 5.422

3.  Taxol provides a second signal for murine macrophage tumoricidal activity.

Authors:  C L Manthey; P Y Perera; C A Salkowski; S N Vogel
Journal:  J Immunol       Date:  1994-01-15       Impact factor: 5.422

4.  Taxol arrests the development of blood-stage Plasmodium falciparum in vitro and Plasmodium chabaudi adami in malaria-infected mice.

Authors:  B Pouvelle; P J Farley; C A Long; T F Taraschi
Journal:  J Clin Invest       Date:  1994-07       Impact factor: 14.808

5.  Interactions between docetaxel (Taxotere) and Plasmodium falciparum-infected erythrocytes.

Authors:  J Schrével; V Sinou; P Grellier; F Frappier; D Guénard; P Potier
Journal:  Proc Natl Acad Sci U S A       Date:  1994-08-30       Impact factor: 11.205

6.  Taxol and lipopolysaccharide activation of a murine macrophage cell line and induction of similar tyrosine phosphoproteins.

Authors:  J M Carboni; C Singh; M A Tepper
Journal:  J Natl Cancer Inst Monogr       Date:  1993

7.  Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase.

Authors:  J D MacMicking; C Nathan; G Hom; N Chartrain; D S Fletcher; M Trumbauer; K Stevens; Q W Xie; K Sokol; N Hutchinson
Journal:  Cell       Date:  1995-05-19       Impact factor: 41.582

8.  Taxol shares the ability of bacterial lipopolysaccharide to induce tyrosine phosphorylation of microtubule-associated protein kinase.

Authors:  A Ding; E Sanchez; C F Nathan
Journal:  J Immunol       Date:  1993-11-15       Impact factor: 5.422

9.  Endotoxin-induced early gene expression in C3H/HeJ (Lpsd) macrophages.

Authors:  C L Manthey; P Y Perera; B E Henricson; T A Hamilton; N Qureshi; S N Vogel
Journal:  J Immunol       Date:  1994-09-15       Impact factor: 5.422

10.  Lipopolysaccharide antagonists block taxol-induced signaling in murine macrophages.

Authors:  C L Manthey; N Qureshi; P L Stütz; S N Vogel
Journal:  J Exp Med       Date:  1993-08-01       Impact factor: 14.307
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  3 in total

1.  Leishmanicidal Activity of Isoselenocyanate Derivatives.

Authors:  Celia Fernández-Rubio; Esther Larrea; José Peña Guerrero; Eduardo Sesma Herrero; Iñigo Gamboa; Carlos Berrio; Daniel Plano; Shantu Amin; Arun K Sharma; Paul A Nguewa
Journal:  Antimicrob Agents Chemother       Date:  2019-01-29       Impact factor: 5.191

2.  Dolabelladienetriol, a compound from Dictyota pfaffii algae, inhibits the infection by Leishmania amazonensis.

Authors:  Deivid Costa Soares; Teresa C Calegari-Silva; Ulisses G Lopes; Valéria L Teixeira; Izabel C N de Palmer Paixão; Claudio Cirne-Santos; Dumith Chequer Bou-Habib; Elvira M Saraiva
Journal:  PLoS Negl Trop Dis       Date:  2012-09-06

3.  Metabolic network analysis predicts efficacy of FDA-approved drugs targeting the causative agent of a neglected tropical disease.

Authors:  Arvind K Chavali; Anna S Blazier; Jose L Tlaxca; Paul A Jensen; Richard D Pearson; Jason A Papin
Journal:  BMC Syst Biol       Date:  2012-04-27
  3 in total

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