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102 in total

1. The novel BCR-ABL and FLT3 inhibitor ponatinib is a potent inhibitor of the MDR-associated ATP-binding cassette transporter ABCG2.

Authors: Rupashree Sen; Karthika Natarajan; Jasjeet Bhullar; Suneet Shukla; Hong-Bin Fang; Ling Cai; Zhe-Sheng Chen; Suresh V Ambudkar; Maria R Baer
Journal: Mol Cancer Ther Date: 2012-07-09 Impact factor: 6.261

2. The "specific" P-glycoprotein inhibitor Tariquidar is also a substrate and an inhibitor for breast cancer resistance protein (BCRP/ABCG2).

Authors: Pavitra Kannan; Sanjay Telu; Suneet Shukla; Suresh V Ambudkar; Victor W Pike; Christer Halldin; Michael M Gottesman; Robert B Innis; Matthew D Hall
Journal: ACS Chem Neurosci Date: 2010-10-21 Impact factor: 4.418

3. Immuno-oncology agent IPI-549 is a modulator of P-glycoprotein (P-gp, MDR1, ABCB1)-mediated multidrug resistance (MDR) in cancer: In vitro and in vivo.

Authors: Albert A De Vera; Pranav Gupta; Zining Lei; Dan Liao; Silpa Narayanan; Qiuxu Teng; Sandra E Reznik; Zhe-Sheng Chen
Journal: Cancer Lett Date: 2018-11-01 Impact factor: 8.679

4. Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5).

Authors: Chung-Pu Wu; Anna Maria Calcagno; Stephen B Hladky; Suresh V Ambudkar; Margery A Barrand
Journal: FEBS J Date: 2005-09 Impact factor: 5.542

5. Global alteration of the drug-binding pocket of human P-glycoprotein (ABCB1) by substitution of fifteen conserved residues reveals a negative correlation between substrate size and transport efficiency.

Authors: Shahrooz Vahedi; Eduardo E Chufan; Suresh V Ambudkar
Journal: Biochem Pharmacol Date: 2017-07-17 Impact factor: 5.858

6. The positive inotropic agent DPI-201106 selectively reverses ABCB1-mediated multidrug resistance in cancer cell lines.

Authors: Sung-Han Hsiao; Megumi Murakami; Ni Yeh; Yan-Qing Li; Tai-Ho Hung; Yu-Shan Wu; Suresh V Ambudkar; Chung-Pu Wu
Journal: Cancer Lett Date: 2018-07-18 Impact factor: 8.679

7. Design, synthesis, and biological evaluation of (S)-valine thiazole-derived cyclic and noncyclic peptidomimetic oligomers as modulators of human P-glycoprotein (ABCB1).

Authors: Satyakam Singh; Nagarajan Rajendra Prasad; Khyati Kapoor; Eduardo E Chufan; Bhargav A Patel; Suresh V Ambudkar; Tanaji T Talele
Journal: Chembiochem Date: 2013-11-29 Impact factor: 3.164

8. Interaction of the multikinase inhibitors sorafenib and sunitinib with solute carriers and ATP-binding cassette transporters.

Authors: Shuiying Hu; Zhaoyuan Chen; Ryan Franke; Shelley Orwick; Ming Zhao; Michelle A Rudek; Alex Sparreboom; Sharyn D Baker
Journal: Clin Cancer Res Date: 2009-09-22 Impact factor: 12.531

9. Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1.

Authors: Yi-Jun Wang; Rishil J Kathawala; Yun-Kai Zhang; Atish Patel; Priyank Kumar; Suneet Shukla; King Leung Fung; Suresh V Ambudkar; Tanaji T Talele; Zhe-Sheng Chen
Journal: Biochem Pharmacol Date: 2014-06-14 Impact factor: 5.858

10. ARRY-334543 reverses multidrug resistance by antagonizing the activity of ATP-binding cassette subfamily G member 2.

Authors: De-Shen Wang; Atish Patel; Hong-May Sim; Yun-Kai Zhang; Yi-Jun Wang; Rishil J Kathawala; Hui Zhang; Tanaji T Talele; Suresh V Ambudkar; Rui-Hua Xu; Zhe-Sheng Chen
Journal: J Cell Biochem Date: 2014-08 Impact factor: 4.429