Literature DB >> 9706090

Control strategies for Marek's disease: a perspective for the future.

R L Witter1.   

Abstract

Marek's disease virus is an evolving pathogen, acquiring virulence in response to increasingly effective vaccines. Although vaccine efficacy is generally good, industry has placed a high priority on more effective products. The search for better vaccines has been conducted mainly in the arena of molecular biology, and has been thus far disappointing. Various conditions prevail that currently limit the potential to develop suitable long-term solutions. A new paradigm based on reduction of early exposure, multiple levels of host resistance, and improved cooperation among stakeholders is proposed for consideration.

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Year:  1998        PMID: 9706090     DOI: 10.1093/ps/77.8.1197

Source DB:  PubMed          Journal:  Poult Sci        ISSN: 0032-5791            Impact factor:   3.352


  15 in total

1.  Characterization of a very virulent Marek's disease virus mutant expressing the pp38 protein from the serotype 1 vaccine strain CVI988/Rispens.

Authors:  Lucy F Lee; Xiaoping Cui; Zhizhong Cui; Isabel Gimeno; Blanca Lupiani; Sanjay M Reddy
Journal:  Virus Genes       Date:  2005-08       Impact factor: 2.332

2.  Growth hormone interacts with the Marek's disease virus SORF2 protein and is associated with disease resistance in chicken.

Authors:  H C Liu; H J Kung; J E Fulton; R W Morgan; H H Cheng
Journal:  Proc Natl Acad Sci U S A       Date:  2001-07-24       Impact factor: 11.205

3.  Integrated analyses of genome-wide DNA occupancy and expression profiling identify key genes and pathways involved in cellular transformation by a Marek's disease virus oncoprotein, Meq.

Authors:  Sugalesini Subramaniam; John Johnston; Likit Preeyanon; C Titus Brown; Hsing-Jien Kung; Hans H Cheng
Journal:  J Virol       Date:  2013-06-05       Impact factor: 5.103

4.  Analysis of transcriptional activities of the Meq proteins present in highly virulent Marek's disease virus strains, RB1B and Md5.

Authors:  Shiro Murata; Tsukasa Okada; Rika Kano; Yuko Hayashi; Tomoyuki Hashiguchi; Misao Onuma; Satoru Konnai; Kazuhiko Ohashi
Journal:  Virus Genes       Date:  2011-04-19       Impact factor: 2.332

Review 5.  Vaccines against Major Poultry Viral Diseases: Strategies to Improve the Breadth and Protective Efficacy.

Authors:  Rajamanonmani Ravikumar; Janlin Chan; Mookkan Prabakaran
Journal:  Viruses       Date:  2022-05-31       Impact factor: 5.818

6.  Clonal structure of rapid-onset MDV-driven CD4+ lymphomas and responding CD8+ T cells.

Authors:  William N Mwangi; Lorraine P Smith; Susan J Baigent; Richard K Beal; Venugopal Nair; Adrian L Smith
Journal:  PLoS Pathog       Date:  2011-05-05       Impact factor: 6.823

7.  Expression of HA of HPAI H5N1 virus at US2 gene insertion site of turkey herpesvirus induced better protection than that at US10 gene insertion site.

Authors:  Hongbo Gao; Hongyu Cui; Xianlan Cui; Xingming Shi; Yan Zhao; Xiaoyan Zhao; Yanming Quan; Shuai Yan; Weiwei Zeng; Yunfeng Wang
Journal:  PLoS One       Date:  2011-07-27       Impact factor: 3.240

8.  Effects of Microbial Aerosol in Poultry House on Meat Ducks' Immune Function.

Authors:  Guanliu Yu; Yao Wang; Shouguo Wang; Changmin Duan; Liangmeng Wei; Jing Gao; Tongjie Chai; Yumei Cai
Journal:  Front Microbiol       Date:  2016-08-17       Impact factor: 5.640

9.  Imperfect Vaccination Can Enhance the Transmission of Highly Virulent Pathogens.

Authors:  Andrew F Read; Susan J Baigent; Claire Powers; Lydia B Kgosana; Luke Blackwell; Lorraine P Smith; David A Kennedy; Stephen W Walkden-Brown; Venugopal K Nair
Journal:  PLoS Biol       Date:  2015-07-27       Impact factor: 8.029

10.  Positive Selection Drives Rapid Evolution of the meq Oncogene of Marek's Disease Virus.

Authors:  Abinash Padhi; Mark S Parcells
Journal:  PLoS One       Date:  2016-09-23       Impact factor: 3.240

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