Literature DB >> 9705925

Lymphocyte signalling: a coordinating role for Vav?

D Cantrell1.   

Abstract

Vav1 is a guanine nucleotide exchange factor that selectively activates the Rac1 GTPase and is expressed specifically in haematopoietic cells. Recent work has revealed how Vav1 integrates signals from lymphocyte antigen receptors and costimulatory receptors to control immune function.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9705925     DOI： 10.1016/s0960-9822(07)00341-7

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  11 in total

Review 1.  Activation and inhibition of lymphocytes by costimulation.

Authors:  Kenneth A Frauwirth; Craig B Thompson
Journal:  J Clin Invest       Date:  2002-02       Impact factor: 14.808

2.  β2 integrin induces TCRζ-Syk-phospholipase C-γ phosphorylation and paxillin-dependent granule polarization in human NK cells.

Authors:  Michael E March; Eric O Long
Journal:  J Immunol       Date:  2011-01-26       Impact factor: 5.422

3.  Central role of protein kinase Cepsilon in constitutive activation of ERK1/2 and Rac1 in the malignant cells of hairy cell leukemia.

Authors:  Joseph R Slupsky; Aura S Kamiguti; Robert J Harris; John C Cawley; Mirko Zuzel
Journal:  Am J Pathol       Date:  2007-02       Impact factor: 4.307

4.  Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex.

Authors:  S P Hehner; T G Hofmann; A Ushmorov; O Dienz; I Wing-Lan Leung; N Lassam; C Scheidereit; W Dröge; M L Schmitz
Journal:  Mol Cell Biol       Date:  2000-04       Impact factor: 4.272

5.  The LMP2A ITAM is essential for providing B cells with development and survival signals in vivo.

Authors:  M Merchant; R G Caldwell; R Longnecker
Journal:  J Virol       Date:  2000-10       Impact factor: 5.103

Review 6.  CD28/CTLA-4 and CD80/CD86 families: signaling and function.

Authors:  J M Slavik; J E Hutchcroft; B E Bierer
Journal:  Immunol Res       Date:  1999       Impact factor: 2.829

Review 7.  Age-related defects in the cytoskeleton signaling pathways of CD4 T cells.

Authors:  Gonzalo G Garcia; Richard A Miller
Journal:  Ageing Res Rev       Date:  2009-11-24       Impact factor: 10.895

Review 8.  Role of phosphoinositide 3-kinase signaling in mast cells: new insights from knockout mouse studies.

Authors:  Taro Fukao; Yasuo Terauchi; Takashi Kadowaki; Shigeo Koyasu
Journal:  J Mol Med (Berl)       Date:  2003-08-19       Impact factor: 4.599

Review 9.  A comprehensive map of the toll-like receptor signaling network.

Authors:  Kanae Oda; Hiroaki Kitano
Journal:  Mol Syst Biol       Date:  2006-04-18       Impact factor: 11.429

10.  The Rho family guanine nucleotide exchange factor Vav-2 regulates the development of cell-mediated cytotoxicity.

Authors:  D D Billadeau; S M Mackie; R A Schoon; P J Leibson
Journal:  J Exp Med       Date:  2000-08-07       Impact factor: 14.307
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.