| Literature DB >> 9705155 |
D Gerdes1, M Wehling, B Leube, E Falkenstein.
Abstract
We have cloned two human putative steroid binding membrane proteins, termed Hpr6.6 and Dg6. Hpr6.6 is the human homolog of a previously cloned porcine progesterone binding protein. Both proteins contain a putative transmembrane domain and a highly conserved stretch of 58 amino acids. Hpr6.6 mRNA is expressed predominantly in liver and kidney, whereas Dg6 mRNA is preferentially expressed in placenta. Hpr6.6 is located on the X chromosome and dg6 on chromosome 4. The two proteins are the first putative steroid membrane receptors cloned from man.Entities:
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Year: 1998 PMID: 9705155 DOI: 10.1515/bchm.1998.379.7.907
Source DB: PubMed Journal: Biol Chem ISSN: 1431-6730 Impact factor: 3.915