Literature DB >> 9704798

May-Hegglin anomaly: a case of vaginal delivery when both mother and fetus are affected.

A C Urato1, J T Repke.   

Abstract

May-Hegglin anomaly is a rare, autosomal dominant disorder characterized by thrombocytopenia and a variable bleeding tendency. In almost all the case reports in the recent literature, platelet transfusion and cesarean section were performed to avoid maternal and neonatal bleeding. We present a case of a woman with May-Hegglin anomaly who had no history of a bleeding tendency. She had a vaginal delivery and a platelet count of 16,000/mm3; the neonate's platelet count was 35,000/mm3. There were no complications. We advocate a reappraisal of basing platelet transfusion and mode of delivery on the platelet count in patients with May-Hegglin anomaly.

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Year:  1998        PMID: 9704798     DOI: 10.1016/s0002-9378(98)70283-2

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  2 in total

1.  The gene for May-Hegglin anomaly localizes to a <1-Mb region on chromosome 22q12.3-13.1.

Authors:  J A Martignetti; K E Heath; J Harris; N Bizzaro; A Savoia; C L Balduini; R J Desnick
Journal:  Am J Hum Genet       Date:  2000-03-17       Impact factor: 11.025

2.  Epidural anesthesia for labor and delivery in a patient with May-Hegglin anomaly: a case report.

Authors:  Annas Muhammad Muzannar; Mohammed Al Harbi; Raza Rathore; Nasser Tawfeeq; Freddie Wambi; Nasir Mahmood; Sonia Albrechtova; Vassilios Dimitriou
Journal:  Local Reg Anesth       Date:  2017-04-28
  2 in total

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