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Literature DB >> 9699460

Gene clusters and polycistronic transcription in eukaryotes.

Abstract

Sometimes genes are arranged nonrandomly on the chromosomes of eukaryotes. This review considers instances of gene clusters in which two genes or more are expressed from a single promoter. This includes cases in which a polycistronic pre-mRNA is processed to make monocistronic mRNAs in nematodes, as well as isolated examples of polycistronic mRNAs found in mammals, flies, and perhaps plants.

Mesh：

Substances：
RNA, Messenger

Year: 1998 PMID： 9699460 DOI： 10.1002/(SICI)1521-1878(199806)20:6<480::AID-BIES6>3.0.CO;2-Q

Source DB: PubMed Journal: Bioessays ISSN： 0265-9247 Impact factor: 4.345

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Cited

58 in total

1. Intercistronic region required for polycistronic pre-mRNA processing in Caenorhabditis elegans.

Authors: T Huang; S Kuersten; A M Deshpande; J Spieth; M MacMorris; T Blumenthal
Journal: Mol Cell Biol Date: 2001-02 Impact factor: 4.272

2. Transcription in archaea.

Authors: N C Kyrpides; C A Ouzounis
Journal: Proc Natl Acad Sci U S A Date: 1999-07-20 Impact factor: 11.205

3. RNA molecules containing exons originating from different members of the cytochrome P450 2C gene subfamily (CYP2C) in human epidermis and liver.

Authors: P G Zaphiropoulos
Journal: Nucleic Acids Res Date: 1999-07-01 Impact factor: 16.971

4. The use of gene clusters to infer functional coupling.

Authors: R Overbeek; M Fonstein; M D'Souza; G D Pusch; N Maltsev
Journal: Proc Natl Acad Sci U S A Date: 1999-03-16 Impact factor: 11.205

Review 5. Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis.

Authors: J Zhao; L Hyman; C Moore
Journal: Microbiol Mol Biol Rev Date: 1999-06 Impact factor: 11.056

6. Dynamical insight into Caenorhabditis elegans eIF4E recognition specificity for mono-and trimethylated structures of mRNA 5' cap.

Authors: Katarzyna Ruszczyńska-Bartnik; Maciej Maciejczyk; Ryszard Stolarski
Journal: J Mol Model Date: 2010-06-10 Impact factor: 1.810

Gene clusters and polycistronic transcription in eukaryotes.

1. Intercistronic region required for polycistronic pre-mRNA processing in Caenorhabditis elegans.

2. Transcription in archaea.

3. RNA molecules containing exons originating from different members of the cytochrome P450 2C gene subfamily (CYP2C) in human epidermis and liver.

4. The use of gene clusters to infer functional coupling.

Review 5. Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis.

6. Dynamical insight into Caenorhabditis elegans eIF4E recognition specificity for mono-and trimethylated structures of mRNA 5' cap.

Review 7. Current methods of gene prediction, their strengths and weaknesses.

8. Transcription-coupled and splicing-coupled strand asymmetries in eukaryotic genomes.

9. A high frequency of overlapping gene expression in compacted eukaryotic genomes.

10. mRNA processing in Antonospora locustae spores.