| Literature DB >> 9699385 |
M de L Chauffaille1, R M Valério, C M Diniz, M M Simões, S Enokihara, N Michalany, K V Ferreira, J A Martinez, K M Hassun, A N Atallah, J Kerbauy.
Abstract
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations. Skin biopsy immunohistochemistry presented positive S100 protein and vimentin, but the diagnosis was done with the demonstration of Birbeck granules with electronic microscopy. The treatment was based on systematical chemotherapy although vulvar lesion has a bad response to chemotherapy.Entities:
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Year: 1998 PMID： 9699385 DOI： 10.1590/s1516-31801998000100006
Source DB: PubMed Journal: Sao Paulo Med J ISSN： 1516-3180 Impact factor: 1.044