Literature DB >> 9697417

N-terminal processing: the methionine aminopeptidase and N alpha-acetyl transferase families.

R A Bradshaw1, W W Brickey, K W Walker.   

Abstract

Removal of the initiator methionine and/or acetylation of the alpha-amino group are among the earliest possible chemical modifications that occur during protein synthesis in eukaryotes. These events are catalyzed by methionine aminopeptidase and N alpha-acetyltransferase, respectively. Recent advances in the isolation and characterization of these enzymes indicate that they exist as isoforms that vary in cellular location, function, and evolutionary origins.

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Year:  1998        PMID： 9697417     DOI： 10.1016/s0968-0004(98)01227-4

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN： 0968-0004            Impact factor:   13.807


  141 in total

1.  Identification of eukaryotic peptide deformylases reveals universality of N-terminal protein processing mechanisms.

Authors:  C Giglione; A Serero; M Pierre; B Boisson; T Meinnel
Journal:  EMBO J       Date:  2000-11-01       Impact factor: 11.598

2.  N-terminal extension changes the folding mechanism of the FK506-binding protein.

Authors:  A Korepanova; C Douglas; I Leyngold; T M Logan
Journal:  Protein Sci       Date:  2001-09       Impact factor: 6.725

3.  Characterization of Ad5 E3-14.7K, an adenoviral inhibitor of apoptosis: structure, oligomeric state, and metal binding.

Authors:  Hee-Jung Kim; Mark P Foster
Journal:  Protein Sci       Date:  2002-05       Impact factor: 6.725

4.  Binding of alpha-hydroxy-beta-amino acid inhibitors to methionine aminopeptidase. The performance of two types of scoring functions.

Authors:  Anne Techau Jørgensen; Morten Dahl Sørensen; Fredrik Björkling; Tommy Liljefors
Journal:  J Comput Aided Mol Des       Date:  2003 May-Jun       Impact factor: 3.686

5.  Investigation of the metal binding site in methionine aminopeptidase by density functional theory.

Authors:  Anne Techau Jørgensen; Per-Ola Norrby; Tommy Liljefors
Journal:  J Comput Aided Mol Des       Date:  2002-03       Impact factor: 3.686

6.  Comparative analysis of the base biases at the gene terminal portions in seven eukaryote genomes.

Authors:  Yoshihito Niimura; Mahito Terabe; Takashi Gojobori; Kin-ichiro Miura
Journal:  Nucleic Acids Res       Date:  2003-09-01       Impact factor: 16.971

7.  Membrane binding properties and terminal residues of the mature hepatitis C virus capsid protein in insect cells.

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Journal:  J Virol       Date:  2004-11       Impact factor: 5.103

8.  Specificity profiling of dual specificity phosphatase vaccinia VH1-related (VHR) reveals two distinct substrate binding modes.

Authors:  Rinrada Luechapanichkul; Xianwen Chen; Hashem A Taha; Shubham Vyas; Xiaoyan Guan; Michael A Freitas; Christopher M Hadad; Dehua Pei
Journal:  J Biol Chem       Date:  2013-01-15       Impact factor: 5.157

9.  Characterization of the active site and insight into the binding mode of the anti-angiogenesis agent fumagillin to the manganese(II)-loaded methionyl aminopeptidase from Escherichia coli.

Authors:  Ventris M D'souza; Robert S Brown; Brian Bennett; Richard C Holz
Journal:  J Biol Inorg Chem       Date:  2004-12-01       Impact factor: 3.358

10.  Mutation of H63 and its catalytic affect on the methionine aminopeptidase from Escherichia coli.

Authors:  Sanghamitra Mitra; Brian Bennett; Richard C Holz
Journal:  Biochim Biophys Acta       Date:  2008-10-07
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