| Literature DB >> 9697186 |
Abstract
A core-promoter, approximately from -60 bp upstream to +40 bp downstream of a RNA polymerase (RNAP) II transcription start site (TSS), binds to the preinitiation complex (PIC) and determine the position of TSS. Using position-specific k-tuple feature variables, a quadratic discriminant analysis (QDA) method is shown to be very effective in identifying human core-promoters.Entities:
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Year: 1998 PMID: 9697186
Source DB: PubMed Journal: Pac Symp Biocomput ISSN: 2335-6928