Literature DB >> 9696974

Comparison of gastric mucosal pH and clinical judgement in critically ill patients.

J T Santoso1, D H Wisner, F D Battistella, J T Owings.   

Abstract

OBJECTIVES: To compare gastric tonometry (pHi) with estimates of pHi in ill injured patients, and to correlate pHi with haemodynamic variables.
DESIGN: Prospective, non-interventional study.
SETTING: ICU of Level I trauma centre, USA. MAIN OUTCOME MEASURES: 154 gastric tonometry measurements were compared with physicians' estimates of adequacy of resuscitation. Resuscitation was categorised as inadequate (pHi < 7.35) or adequate (pHi> or = 7.35). Measured and estimated pHi were also compared with oxygen delivery, oxygen consumption, cardiac index, mixed venous O2 saturation, and critical illness scores.
RESULTS: Estimated pHi was often higher than measured pHi in the judgement of all four surgical intensive care physicians. Measured pHi correlated positively with mixed venous O2 tension (r = 0.21). There were significant negative correlations between measured pHi and both oxygen delivery (r = -0.25) and oxygen consumption (r = 0.28). Estimated pHi correlated positively with mean arterial pressure (r = 0.21) and hospital day (r = 0.26); it correlated negatively with pulmonary arterial elastance (r = -0.35).
CONCLUSION: Experienced intensive care physicians tended to overestimate visceral perfusion, which suggests that gastric tonometry adds useful information over and above routine haemodynamic indices. Arterial blood pressure and mixed venous oxygen saturation correlated better with measured pHi than with other indices of perfusion.

Entities:  

Mesh:

Substances:

Year:  1998        PMID: 9696974     DOI: 10.1080/110241598750005877

Source DB:  PubMed          Journal:  Eur J Surg        ISSN: 1102-4151


  3 in total

1.  Effect of shenfu injection on gastrointestinal microcirculation in rabbits after myocardial ischemia-reperfusion injury.

Authors:  Xue-Juan Zhang; Li Song; Zan-Gong Zhou; Xiu-Mei Wang
Journal:  World J Gastroenterol       Date:  2006-07-21       Impact factor: 5.742

2.  Gastric Tonometry as a Prognostic Index of Mortality in Sepsis.

Authors:  K K Upadhyay; V P Singh; Tvsp Murthy
Journal:  Med J Armed Forces India       Date:  2011-07-21

3.  The role of the intestine in the pathophysiology and management of severe acute pancreatitis.

Authors:  R S Flint; J A Windsor
Journal:  HPB (Oxford)       Date:  2003       Impact factor: 3.647

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.