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Literature DB >> 9696362

In situ hybridization: a possible diagnostic aid in leptomeningeal metastasis.

R J van Oostenbrugge¹, A H Hopman, F C Ramaekers, A Twijnstra.

Abstract

In this review we discuss the clinical features and pathophysiology of leptomeningeal metastasis (LM), and elaborate on diagnostic tools for the detection of this serious complication of cancer. Because of the low sensitivity of the cytologic examination, new diagnostic approaches have been developed. The in situ hybridization technique may prove to be a reliable and early test for the detection of LM.

Entities: Disease

Mesh：

Substances：
DNA, Neoplasm

Year: 1998 PMID： 9696362 DOI： 10.1023/a:1005926624303

Source DB: PubMed Journal: J Neurooncol ISSN： 0167-594X Impact factor: 4.130

51 in total

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6 in total

Review 1. Leukemia and the nervous system.

Authors: Marc C Chamberlain
Journal: Curr Oncol Rep Date: 2005-01 Impact factor: 5.075

Review 5. Neoplastic meningitis.

Authors: Ana Aparicio; Marc C Chamberlain
Journal: Curr Neurol Neurosci Rep Date: 2002-05 Impact factor: 5.081

Review 6. Neoplastic meningitis.

Authors: Marc C Chamberlain
Journal: Curr Neurol Neurosci Rep Date: 2008-05 Impact factor: 5.081