Literature DB >> 9696089

The pathogenesis of arteriovenous malformations: insights provided by a case of multiple arteriovenous malformations developing in relation to a developmental venous anomaly.

E S Nussbaum1, R C Heros, M T Madison, D Awasthi, C L Truwit.   

Abstract

OBJECTIVE AND IMPORTANCE: Developmental venous anomalies (DVAs) are common anomalies of intracranial venous drainage that may occur in conjunction with other cerebral vascular malformations. The present case raises important questions regarding the association between anomalous venous drainage patterns and the development of arteriovenous malformations (AVMs). CLINICAL
PRESENTATION: We present the case of a 24-year-old man with small AVMs fed by the superior cerebellar artery that drained directly into a large DVA of the cerebellum. INTERVENTION: The patient was managed conservatively and returned 10 years later with recurrent symptoms. A repeat angiogram demonstrated spontaneous thrombosis of the previously documented AVMs; however, new AVMs at a different site that was also fed by the superior cerebellar artery and drained into the same DVA had appeared. The AVMs were completely embolized, and the DVA was left intact.
CONCLUSION: Recently, increasing attention has focused on the possible importance of venous outflow disturbance and venous hypertension in the pathogenesis and pathophysiology of AVMs. The potential mechanisms for this association and the implications of the present case are discussed, and the pertinent literature is reviewed.

Entities:  

Mesh:

Year:  1998        PMID: 9696089     DOI: 10.1097/00006123-199808000-00103

Source DB:  PubMed          Journal:  Neurosurgery        ISSN: 0148-396X            Impact factor:   4.654


  11 in total

Review 1.  Cerebral developmental venous anomalies.

Authors:  Diego San Millán Ruíz; Philippe Gailloud
Journal:  Childs Nerv Syst       Date:  2010-08-12       Impact factor: 1.475

Review 2.  De novo cerebral arteriovenous malformation: case report and literature review.

Authors:  J Stevens; J L Leach; T Abruzzo; B V Jones
Journal:  AJNR Am J Neuroradiol       Date:  2008-09-03       Impact factor: 3.825

3.  Developmental venous anomaly in the newborn brain.

Authors:  S Horsch; P Govaert; F M Cowan; M J N L Benders; F Groenendaal; M H Lequin; G Saliou; L S de Vries
Journal:  Neuroradiology       Date:  2014-04-23       Impact factor: 2.804

4.  The effect of age on arteriovenous malformations in children and young adults undergoing magnetic resonance imaging.

Authors:  Thomas M O'Lynnger; Wajd N Al-Holou; Joseph J Gemmete; Aditya S Pandey; B Gregory Thompson; Hugh J L Garton; Cormac O Maher
Journal:  Childs Nerv Syst       Date:  2011-03-26       Impact factor: 1.475

5.  Venous angiomas.

Authors:  Sepideh Amin-Hanjani
Journal:  Curr Treat Options Cardiovasc Med       Date:  2011-06

6.  Developmental venous anomalies with capillary stain: a subgroup of symptomatic DVAs?

Authors:  Luca Roccatagliata; René van den Berg; Michael Soderman; Anne Boulin; Stéphanie Condette-Auliac; Georges Rodesch
Journal:  Neuroradiology       Date:  2011-06-11       Impact factor: 2.804

7.  Developmental venous anomaly (DVA) with arterial component: a rare cause of intracranial haemorrhage.

Authors:  Ismail Oran; Yilmaz Kiroglu; Alaattin Yurt; Fisun Demircivi Ozer; Feridun Acar; Tayfun Dalbasti; Baki Yagci; Akif Sirikci; Cem Calli
Journal:  Neuroradiology       Date:  2008-09-12       Impact factor: 2.804

8.  Nonischemic cerebral venous hypertension promotes a pro-angiogenic stage through HIF-1 downstream genes and leukocyte-derived MMP-9.

Authors:  Peng Gao; Yiqian Zhu; Feng Ling; Fanxia Shen; Brian Lee; Rodney Allanigue Gabriel; Qi Hao; Guo-Yuan Yang; Hua Su; William L Young
Journal:  J Cereb Blood Flow Metab       Date:  2009-05-27       Impact factor: 6.200

9.  Symptomatic de novo arteriovenous malformation in an adult: Case report and review of the literature.

Authors:  Jayson A Neil; Daphne Li; Michael F Stiefel; Yin C Hu
Journal:  Surg Neurol Int       Date:  2014-10-13

Review 10.  Developmental Venous Anomaly: Benign or Not Benign.

Authors:  Rie Aoki; Kittipong Srivatanakul
Journal:  Neurol Med Chir (Tokyo)       Date:  2016-06-01       Impact factor: 1.742

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