Literature DB >> 9695848

Proteolytic ratchets that control progression through mitosis.

F M Townsley1, J V Ruderman2.   

Abstract

A key player in mitotic progression is a cell-cycle-regulated ubiquitin-protein ligase complex known as the anaphase-promoting complex or cyclosome (APC/C). The APC/C is part of the machinery that promotes the metaphase-anaphase transition by mediating the ubiquitin-dependent destruction of anaphase inhibitors and initiates exit from mitosis by degrading mitotic cyclins. This review describes the known components and substrates of the mitotic ubiquitination machinery and discusses how a new subfamily of proteins that contain the WD40 repeat (the Fizzy/Cdc20p family) might activate the APC/C to allow temporal differences in substrate ubiquitination during progression through mitosis.

Entities:  

Mesh：

Substances：

Year:  1998        PMID： 9695848     DOI： 10.1016/s0962-8924(98)01268-9

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  30 in total

1.  Cell cycle control of Cdc7p kinase activity through regulation of Dbf4p stability.

Authors:  G Oshiro; J C Owens; Y Shellman; R A Sclafani; J J Li
Journal:  Mol Cell Biol       Date:  1999-07       Impact factor: 4.272

2.  Clink, a nanovirus-encoded protein, binds both pRB and SKP1.

Authors:  M N Aronson; A D Meyer; J Györgyey; L Katul; H J Vetten; B Gronenborn; T Timchenko
Journal:  J Virol       Date:  2000-04       Impact factor: 5.103

3.  Hypomorphic bimA(APC3) alleles cause errors in chromosome metabolism that activate the DNA damage checkpoint blocking cytokinesis in Aspergillus nidulans.

Authors:  T D Wolkow; P M Mirabito; S Venkatram; J E Hamer
Journal:  Genetics       Date:  2000-01       Impact factor: 4.562

4.  The disappearance of cyclin B at the end of mitosis is regulated spatially in Drosophila cells.

Authors:  J Huang; J W Raff
Journal:  EMBO J       Date:  1999-04-15       Impact factor: 11.598

Review 5.  Regulation of cyclin-dependent kinases in Arabidopsis thaliana.

Authors:  H Stals; P Casteels; M Van Montagu; D Inzé
Journal:  Plant Mol Biol       Date:  2000-08       Impact factor: 4.076

6.  Cell cycle-dependent expression of mammalian E2-C regulated by the anaphase-promoting complex/cyclosome.

Authors:  A Yamanaka; S Hatakeyama; K Kominami; M Kitagawa; M Matsumoto; K Nakayama
Journal:  Mol Biol Cell       Date:  2000-08       Impact factor: 4.138

7.  Identification of an overlapping binding domain on Cdc20 for Mad2 and anaphase-promoting complex: model for spindle checkpoint regulation.

Authors:  Y Zhang; E Lees
Journal:  Mol Cell Biol       Date:  2001-08       Impact factor: 4.272

8.  Cell cycle transition under stress conditions controlled by vertebrate heat shock factors.

Authors:  A Nakai; T Ishikawa
Journal:  EMBO J       Date:  2001-06-01       Impact factor: 11.598

9.  A nonproteolytic function of the proteasome is required for the dissociation of Cdc2 and cyclin B at the end of M phase.

Authors:  A Nishiyama; K Tachibana; Y Igarashi; H Yasuda; N Tanahashi; K Tanaka; K Ohsumi; T Kishimoto
Journal:  Genes Dev       Date:  2000-09-15       Impact factor: 11.361

10.  Mechanism of Aurora-B degradation and its dependency on intact KEN and A-boxes: identification of an aneuploidy-promoting property.

Authors:  Hao G Nguyen; Dharmaraj Chinnappan; Takeshi Urano; Katya Ravid
Journal:  Mol Cell Biol       Date:  2005-06       Impact factor: 4.272
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.