Literature DB >> 9695830

Surfing on a retrograde wave: how does Shiga toxin reach the endoplasmic reticulum?

L Johannes1, B Goud.   

Abstract

Bacterial Shiga toxin and related toxins are endocytosed by higher eukaryotic cells. The toxin protein is then transported via the Golgi apparatus to the endoplasmic reticulum (ER) and into the cytosol, where it exerts its toxic effect. This review discusses current understanding of this retrograde transport pathway and how newly developed modified toxins that allow detection and quantification of specific transport steps might prove useful tools in the future.

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Year:  1998        PMID： 9695830     DOI： 10.1016/s0962-8924(97)01209-9

Source DB:  PubMed          Journal:  Trends Cell Biol        ISSN： 0962-8924            Impact factor:   20.808


  22 in total

1.  The p21 Rho-activating toxin cytotoxic necrotizing factor 1 is endocytosed by a clathrin-independent mechanism and enters the cytosol by an acidic-dependent membrane translocation step.

Authors:  S Contamin; A Galmiche; A Doye; G Flatau; A Benmerah; P Boquet
Journal:  Mol Biol Cell       Date:  2000-05       Impact factor: 4.138

2.  Cellular internalization of cytolethal distending toxin from Haemophilus ducreyi.

Authors:  X Cortes-Bratti; E Chaves-Olarte; T Lagergård; M Thelestam
Journal:  Infect Immun       Date:  2000-12       Impact factor: 3.441

3.  Targeting of Shiga toxin B-subunit to retrograde transport route in association with detergent-resistant membranes.

Authors:  T Falguières; F Mallard; C Baron; D Hanau; C Lingwood; B Goud; J Salamero; L Johannes
Journal:  Mol Biol Cell       Date:  2001-08       Impact factor: 4.138

4.  Alpha(1)-Antitrypsin Deficiency.

Authors: 
Journal:  Curr Treat Options Gastroenterol       Date:  2000-12

5.  Shiga toxin is transported from the endoplasmic reticulum following interaction with the luminal chaperone HEDJ/ERdj3.

Authors:  Min Yu; David B Haslam
Journal:  Infect Immun       Date:  2005-04       Impact factor: 3.441

6.  Regulation of protein transport from the Golgi complex to the endoplasmic reticulum by CDC42 and N-WASP.

Authors:  Ana Luna; Olga B Matas; José Angel Martínez-Menárguez; Eugenia Mato; Juan M Durán; José Ballesta; Michael Way; Gustavo Egea
Journal:  Mol Biol Cell       Date:  2002-03       Impact factor: 4.138

7.  Cytotoxic and apoptotic effects of recombinant subtilase cytotoxin variants of shiga toxin-producing Escherichia coli.

Authors:  J Funk; N Biber; M Schneider; E Hauser; S Enzenmüller; C Förtsch; H Barth; H Schmidt
Journal:  Infect Immun       Date:  2015-03-30       Impact factor: 3.441

8.  Saturation of the endoplasmic reticulum retention machinery reveals anterograde bulk flow

Authors: 
Journal:  Plant Cell       Date:  1999-11       Impact factor: 11.277

9.  The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer.

Authors:  Michael A Rycyzyn; Charles V Clevenger
Journal:  Proc Natl Acad Sci U S A       Date:  2002-05-07       Impact factor: 11.205

Review 10.  Cholesterol regulation of rab-mediated sphingolipid endocytosis.

Authors:  Miwa Takahashi; Toshihide Kobayashi
Journal:  Glycoconj J       Date:  2008-10-08       Impact factor: 2.916
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