Literature DB >> 9695086

Eye malformations associated with treatment with carbamazepine during pregnancy.

A G Sutcliffe1, R B Jones, G Woodruff.   

Abstract

Four children are presented and their eye malformations described. One girl had bilateral anophthalmos, a boy and a girl had bilateral severe microphthalmos, and a boy had a unilateral optic disc coloboma. The mothers of all for children were treated with carbamazepine during pregnancy. The teratogenic effect of carbamazepine and its likely role in the genesis of the eye malformations is discussed.

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Year:  1998        PMID： 9695086     DOI： 10.1076/opge.19.2.59.2321

Source DB:  PubMed          Journal:  Ophthalmic Genet        ISSN： 1381-6810            Impact factor:   1.803


  4 in total

Review 1.  Ocular coloboma: a reassessment in the age of molecular neuroscience.

Authors:  C Y Gregory-Evans; M J Williams; S Halford; K Gregory-Evans
Journal:  J Med Genet       Date:  2004-12       Impact factor: 6.318

2.  A clinical study of 57 children with fetal anticonvulsant syndromes.

Authors:  S J Moore; P Turnpenny; A Quinn; S Glover; D J Lloyd; T Montgomery; J C Dean
Journal:  J Med Genet       Date:  2000-07       Impact factor: 6.318

Review 3.  Review of evidence for environmental causes of uveal coloboma.

Authors:  Evan B Selzer; Delphine Blain; Robert B Hufnagel; Philip J Lupo; Laura E Mitchell; Brian P Brooks
Journal:  Surv Ophthalmol       Date:  2021-12-31       Impact factor: 6.197

4.  Ocular coloboma and foetal valproate syndrome: four further cases and a hypothesis for aetiology.

Authors:  Adam Jackson; Alan Fryer; Virginia Clowes; Jill Clayton-Smith
Journal:  Clin Dysmorphol       Date:  2014-04       Impact factor: 0.816
  4 in total

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