Literature DB >> 9693631

Use of an oral antiseptic bioadhesive tablet in dogs.

P Gruet1, C Gaillard, B Boisramé, D Duffaut, A M Grimoud, G Camy.   

Abstract

V3703 (Stomadhex) is a tablet with bioadhesive properties enabling it to remain in place for several hours after it has been placed on the oral mucosa. It continuously releases chlorhexidine and niacinamide. In a study conducted in 15 dogs, the tablets were well tolerated by the animals. The product significantly reduced (p < 0.05): dental plaque; quantitative periodontopathogen and total anaerobic bacterial counts; spirochetes; and halitosis when used daily over a 14 day period. Gingivitis was also reduced, though not significantly (p = 0.07). Stomadhex treatment can provide a carry-over effect following dental scaling by reducing oral microflora and retarding the reappearance of dental plaque.

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Year:  1995        PMID: 9693631

Source DB:  PubMed          Journal:  J Vet Dent        ISSN: 0898-7564            Impact factor:   0.857


  1 in total

1.  Prevention of drug carryover effects in studies assessing antimycobacterial efficacy of TMC207.

Authors:  Nacer Lounis; Tom Gevers; Joke Van Den Berg; Tom Verhaeghe; Rolf van Heeswijk; Koen Andries
Journal:  J Clin Microbiol       Date:  2008-05-14       Impact factor: 5.948

  1 in total

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