| Literature DB >> 9693190 |
T Kobayashi1, K Sakuraoka, M Iwamoto, S Kurihara.
Abstract
A 10-year-old Japanese male with multiple blister formation and palpable purpura in the course of anaphylactoid purpura is described. Histologically, the lesions showed leukocytoclastic vasculitis in the upper dermis with subepidermal clefts. Blister fluid showed matrix metalloproteinase (MMP) 2 and MMP-9 gelantinolytic activities using zymography. These enzymatic reactions, especially that involving MMP-9 derived from polymorphonuclear leukocytes, might play an important role in the pathophysiology of this condition.Entities:
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Year: 1998 PMID： 9693190 DOI： 10.1159/000017959
Source DB: PubMed Journal: Dermatology ISSN： 1018-8665 Impact factor: 5.366