Literature DB >> 9691067

Combinatorial protein design by in vitro recombination.

L Giver1, F H Arnold.   

Abstract

DNA recombination is a powerful engine for the creation of new phenotypes. Recently, methods for in vitro DNA recombination (DNA shuffling) have been developed and applied to the evolution of novel molecules in the laboratory. An exciting new development is the shuffling of homologous genes to create diversity for directed evolution.

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Year:  1998        PMID： 9691067     DOI： 10.1016/s1367-5931(98)80006-9

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  9 in total

1.  Bacterial cell surface display of an enzyme library for selective screening of improved cellulase variants.

Authors:  Y S Kim; H C Jung; J G Pan
Journal:  Appl Environ Microbiol       Date:  2000-02       Impact factor: 4.792

2.  High efficiency family shuffling based on multi-step PCR and in vivo DNA recombination in yeast: statistical and functional analysis of a combinatorial library between human cytochrome P450 1A1 and 1A2.

Authors:  V Abécassis; D Pompon; G Truan
Journal:  Nucleic Acids Res       Date:  2000-10-15       Impact factor: 16.971

3.  Adaptive impact of the chimeric gene Quetzalcoatl in Drosophila melanogaster.

Authors:  Rebekah L Rogers; Trevor Bedford; Ana M Lyons; Daniel L Hartl
Journal:  Proc Natl Acad Sci U S A       Date:  2010-06-01       Impact factor: 11.205

4.  Designability of alpha-helical proteins.

Authors:  Eldon G Emberly; Ned S Wingreen; Chao Tang
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-12       Impact factor: 11.205

Review 5.  Laboratory-directed protein evolution.

Authors:  Ling Yuan; Itzhak Kurek; James English; Robert Keenan
Journal:  Microbiol Mol Biol Rev       Date:  2005-09       Impact factor: 11.056

6.  Formation and longevity of chimeric and duplicate genes in Drosophila melanogaster.

Authors:  Rebekah L Rogers; Trevor Bedford; Daniel L Hartl
Journal:  Genetics       Date:  2008-11-17       Impact factor: 4.562

7.  Chimeric genes as a source of rapid evolution in Drosophila melanogaster.

Authors:  Rebekah L Rogers; Daniel L Hartl
Journal:  Mol Biol Evol       Date:  2011-07-18       Impact factor: 16.240

8.  Tandem Duplications and the Limits of Natural Selection in Drosophila yakuba and Drosophila simulans.

Authors:  Rebekah L Rogers; Julie M Cridland; Ling Shao; Tina T Hu; Peter Andolfatto; Kevin R Thornton
Journal:  PLoS One       Date:  2015-07-15       Impact factor: 3.240

9.  Evolution of a novel chimeric maltotriose transporter in Saccharomyces eubayanus from parent proteins unable to perform this function.

Authors:  EmilyClare P Baker; Chris Todd Hittinger
Journal:  PLoS Genet       Date:  2019-04-04       Impact factor: 5.917
  9 in total

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