Literature DB >> 9689735

Prevention of diarrhoea using pathogen specific monoclonal antibodies in an experimental enterotoxigenic E. coli infection in germfree piglets.

B de Geus1, M Harmsen, F van Zijderveld.   

Abstract

In the present study we describe the effect of oral application of mAB specific for ETEC F4ac fimbriae in an experimental ETEC challenge model in neonatal germfree piglets. The results show that mAB, specific for different F4ac epitopes protect animals against ETEC specific pathology. Moreover, the results show that protection is independent of F4ac epitope specificity.

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Year:  1998        PMID： 9689735

Source DB:  PubMed          Journal:  Vet Q        ISSN： 0165-2176            Impact factor:   3.320


  5 in total

1.  Orally fed seeds producing designer IgAs protect weaned piglets against enterotoxigenic Escherichia coli infection.

Authors:  Vikram Virdi; Annelies Coddens; Sylvie De Buck; Sam Millet; Bruno Maria Goddeeris; Eric Cox; Henri De Greve; Ann Depicker
Journal:  Proc Natl Acad Sci U S A       Date:  2013-06-25       Impact factor: 11.205

2.  Competitive exclusion treatment reduces the mortality and fecal shedding associated with enterotoxigenic Escherichia coli infection in nursery-raised neonatal pigs.

Authors:  K J Genovese; R C Anderson; R B Harvey; D J Nisbet
Journal:  Can J Vet Res       Date:  2000-10       Impact factor: 1.310

3.  Orally administered P22 phage tailspike protein reduces salmonella colonization in chickens: prospects of a novel therapy against bacterial infections.

Authors:  Shakeeba Waseh; Pejman Hanifi-Moghaddam; Russell Coleman; Michael Masotti; Shannon Ryan; Mary Foss; Roger MacKenzie; Matthew Henry; Christine M Szymanski; Jamshid Tanha
Journal:  PLoS One       Date:  2010-11-22       Impact factor: 3.240

4.  Orally active bivalent VHH construct prevents proliferation of F4+ enterotoxigenic Escherichia coli in weaned piglets.

Authors:  Berthe Katrine Fiil; Sandra Wingaard Thrane; Michael Pichler; Tiia Kittilä; Line Ledsgaard; Shirin Ahmadi; Grith Miriam Maigaard Hermansen; Lars Jelsbak; Charlotte Lauridsen; Susanne Brix; Andreas Hougaard Laustsen
Journal:  iScience       Date:  2022-03-01

Review 5.  Single Domain Antibody application in bacterial infection diagnosis and neutralization.

Authors:  Qian Qin; Hao Liu; Wenbo He; Yucheng Guo; Jiaxin Zhang; Junjun She; Fang Zheng; Sicai Zhang; Serge Muyldermans; Yurong Wen
Journal:  Front Immunol       Date:  2022-09-29       Impact factor: 8.786
  5 in total

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