Literature DB >> 9688457

Peroxynitrite: a biologically significant oxidant.

M P Murphy1, M A Packer, J L Scarlett, S W Martin.   

Abstract

1. Peroxynitrite is a short-lived and damaging oxidant that forms rapidly from the reaction of superoxide with nitric oxide. 2. In 1990, Joseph Beckman proposed that peroxynitrite contributed significantly to pathological oxidative stress in living tissues, and subsequent evidence strongly supports this proposal. 3. In this review, we outline the properties of peroxynitrite and discuss how it can affect biological systems and contribute to human pathologies.

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Year:  1998        PMID: 9688457     DOI: 10.1016/s0306-3623(97)00418-7

Source DB:  PubMed          Journal:  Gen Pharmacol        ISSN: 0306-3623


  23 in total

1.  Physiologically relevant oxidative degradation of oligo(proline) cross-linked polymeric scaffolds.

Authors:  Shann S Yu; Rachel L Koblin; Angela L Zachman; Daniel S Perrien; Lucas H Hofmeister; Todd D Giorgio; Hak-Joon Sung
Journal:  Biomacromolecules       Date:  2011-10-31       Impact factor: 6.988

2.  Vitamins inhibit oxidant-induced apoptosis of corneal endothelial cells.

Authors:  Nermin Serbecic; Sven Christoph Beutelspacher
Journal:  Jpn J Ophthalmol       Date:  2005 Sep-Oct       Impact factor: 2.447

Review 3.  Interaction between glutathione and apoptosis in systemic lupus erythematosus.

Authors:  Dilip Shah; Sangita Sah; Swapan K Nath
Journal:  Autoimmun Rev       Date:  2012-12-29       Impact factor: 9.754

4.  EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology.

Authors:  Y Rong; S R Doctrow; G Tocco; M Baudry
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-17       Impact factor: 11.205

5.  Kinetic modeling of nitric-oxide-associated reaction network.

Authors:  Teh-Min Hu; William L Hayton; Susan R Mallery
Journal:  Pharm Res       Date:  2006-08       Impact factor: 4.200

Review 6.  Repression of gene expression by oxidative stress.

Authors:  Y Morel; R Barouki
Journal:  Biochem J       Date:  1999-09-15       Impact factor: 3.857

Review 7.  Pyruvate dehydrogenase complex: metabolic link to ischemic brain injury and target of oxidative stress.

Authors:  Erica Martin; Robert E Rosenthal; Gary Fiskum
Journal:  J Neurosci Res       Date:  2005 Jan 1-15       Impact factor: 4.164

Review 8.  Roles of amyloid beta-peptide-associated oxidative stress and brain protein modifications in the pathogenesis of Alzheimer's disease and mild cognitive impairment.

Authors:  D Allan Butterfield; Tanea Reed; Shelley F Newman; Rukhsana Sultana
Journal:  Free Radic Biol Med       Date:  2007-06-13       Impact factor: 7.376

9.  The contribution of N₂O₃ to the cytotoxicity of the nitric oxide donor DETA/NO: an emerging role for S-nitrosylation.

Authors:  Ahlam A Ali; Jonathan A Coulter; Claire H Ogle; Marie M Migaud; David G Hirst; Tracy Robson; Helen O McCarthy
Journal:  Biosci Rep       Date:  2013-03-28       Impact factor: 3.840

Review 10.  Use of fluorescence probes for detection of reactive nitrogen species: a review.

Authors:  Ana Gomes; Eduarda Fernandes; José L F C Lima
Journal:  J Fluoresc       Date:  2006-01       Impact factor: 2.217

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