An efficient Fourier method for 3-D radon inversion in exact cone-beam CT reconstruction.

The radial derivative of the three-dimensional (3-D) radon transform of an object is an important intermediate result in many analytically exact cone-beam reconstruction algorithms. We briefly review Grangeat's approach for calculating radon derivative data from cone-beam projections and then present a new, efficient method for 3-D radon inversion, i.e., reconstruction of the image from the radial derivative of the 3-D radon transform, called direct Fourier inversion (DFI). The method is based directly on the 3-D Fourier slice theorem. From the 3-D radon derivative data, which is assumed to be sampled on a spherical grid, the 3-D Fourier transform of the object is calculated by performing fast Fourier transforms (FFT's) along radial lines in the radon space. Then, an interpolation is performed from the spherical to a Cartesian grid using a 3-D gridding step in the frequency domain. Finally, this 3-D Fourier transform is transformed back to the spatial domain via 3-D inverse FFT. The algorithm is computationally efficient with complexity in the order of N3 logN. We have done reconstructions of simulated 3-D radon derivative data assuming sampling conditions and image quality requirements similar to those in medical computed tomography (CT).