Literature DB >> 96878

Relationship between anorectic and reinforcing properties of appetite suppressant drugs: implications for assessment of abuse liability.

R R Griffiths, J V Brady, J D Snell.   

Abstract

A quantitative ratio measure was developed which permitted comparisons between the reinforcing and anorectic potency of eight phenylethylamine anorectics and cocaine in laboratory baboons. The ordering of these compounds based upon this ratio bears a reasonable correspondence to clinical drug evaluations. The measure may provide information for preclinical evaluation of relative abuse potential of anorectic drugs.

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Year:  1978        PMID: 96878

Source DB:  PubMed          Journal:  Biol Psychiatry        ISSN: 0006-3223            Impact factor:   13.382


  11 in total

1.  Progressive ratio and fixed ratio schedules of cocaine-maintained responding in baboons.

Authors:  R R Griffiths; L D Bradford; J V Brady
Journal:  Psychopharmacology (Berl)       Date:  1979-10       Impact factor: 4.530

Review 2.  The behavioral pharmacology of anorexigenic drugs in nonhuman primates: 30 years of progress.

Authors:  Richard W Foltin
Journal:  Behav Pharmacol       Date:  2012-09       Impact factor: 2.293

3.  Should sympathomimetics be available over the counter?

Authors:  J P Morgan
Journal:  Br Med J (Clin Res Ed)       Date:  1987-10-10

4.  Self-administration in baboons and the discriminative stimulus effects in rats of bupropion, nomifensine, diclofensine and imipramine.

Authors:  R J Lamb; R R Griffiths
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

5.  Effects of the dopamine/norepinephrine releaser phenmetrazine on cocaine self-administration and cocaine-primed reinstatement in rats.

Authors:  Paul W Czoty; Phuong Tran; Leanne N Thomas; Thomas J Martin; Amanda Grigg; Bruce E Blough; Thomas J R Beveridge
Journal:  Psychopharmacology (Berl)       Date:  2015-02-13       Impact factor: 4.530

Review 6.  Animal models of drug craving.

Authors:  A Markou; F Weiss; L H Gold; S B Caine; G Schulteis; G F Koob
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

7.  Self-injection of barbiturates and benzodiazepines in baboons.

Authors:  R R Griffiths; S E Lukas; L D Bradford; J V Brady; J D Snell
Journal:  Psychopharmacology (Berl)       Date:  1981       Impact factor: 4.530

8.  Self-injection of d,1-3,4-methylenedioxymethamphetamine (MDMA) in the baboon.

Authors:  R J Lamb; R R Griffiths
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

9.  Phenylpropanolamine: reinforcing and subjective effects in normal human volunteers.

Authors:  L D Chait; E H Uhlenhuth; C E Johanson
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

10.  Similarities between the stimulus properties of phenylpropanolamine and amphetamine.

Authors:  F Lee; I Stafford; B G Hoebel
Journal:  Psychopharmacology (Berl)       Date:  1989       Impact factor: 4.530

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