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Literature DB >> 9687424

In vitro activities of the ketolide HMR 3647 against recent gram-positive clinical isolates and Haemophilus influenzae.

Abstract

The ketolide HMR 3647 (previously RU 66647) was evaluated against 2, 563 recent clinical isolates of gram-positive pathogens and 200 Haemophilus influenzae isolates. HMR 3647 was active against macrolide-resistant streptococci, including pneumococci, but was not active against macrolide- or lincosamide-resistant staphylococci. Against H. influenzae, the potency of HMR 3647 was similar to that of azithromycin.

Entities: Chemical Species

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Year: 1998 PMID： 9687424 PMCID： PMC105887

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

8 in total

1. Antipneumococcal activities of a ketolide (HMR 3647), a streptogramin (quinupristin-dalfopristin), a macrolide (erythromycin), and a lincosamide (clindamycin).

Authors: A L Barry; P C Fuchs; S D Brown
Journal: Antimicrob Agents Chemother Date: 1998-04 Impact factor: 5.191

2. In vitro activity of the new ketolide HMR 3004 compared to an azalide and macrolides against Streptococcus pneumoniae and Haemophilus influenzae.

Authors: A L Barry; P C Fuchs; S D Brown
Journal: Eur J Clin Microbiol Infect Dis Date: 1997-10 Impact factor: 3.267

3. Antibacterial activity of RU 64004 (HMR 3004), a novel ketolide derivative active against respiratory pathogens.

Authors: C Agouridas; A Bonnefoy; J F Chantot
Journal: Antimicrob Agents Chemother Date: 1997-10 Impact factor: 5.191

4. Comparative antianaerobic activities of the ketolides HMR 3647 (RU 66647) and HMR 3004 (RU 64004).

Authors: L M Ednie; M R Jacobs; P C Appelbaum
Journal: Antimicrob Agents Chemother Date: 1997-09 Impact factor: 5.191

5. Macrolide resistance among Streptococcus pneumoniae and Streptococcus pyogenes isolates from out-patients in the USA.

Authors: A L Barry; P C Fuchs; S D Brown
Journal: J Antimicrob Chemother Date: 1997-07 Impact factor: 5.790

6. In vitro activity of RU 64004, a new ketolide antibiotic, against gram-positive bacteria.

Authors: T Schülin; C B Wennersten; R C Moellering; G M Eliopoulos
Journal: Antimicrob Agents Chemother Date: 1997-05 Impact factor: 5.191

7. In vitro evaluation of a novel ketolide antimicrobial agent, RU-64004.

Authors: C Jamjian; D J Biedenbach; R N Jones
Journal: Antimicrob Agents Chemother Date: 1997-02 Impact factor: 5.191

8. Antimicrobial activity of RU-66647, a new ketolide.

Authors: R N Jones; D J Biedenbach
Journal: Diagn Microbiol Infect Dis Date: 1997 Jan-Feb Impact factor: 2.803

8 in total

20 in total

1. In vitro activity of ABT 773, a new ketolide antibiotic, against Chlamydia pneumoniae.

Authors: S Strigl; P M Roblin; T Reznik; M R Hammerschlag
Journal: Antimicrob Agents Chemother Date: 2000-04 Impact factor: 5.191

2. In vitro activity of the ketolide ABT-773.

Authors: A L Barry; P C Fuchs; S D Brown
Journal: Antimicrob Agents Chemother Date: 2001-10 Impact factor: 5.191

3. Intrapulmonary pharmacokinetics of telithromycin, a new ketolide, in healthy Japanese volunteers.

Authors: Jun-Ichi Kadota; Yuji Ishimatsu; Tetsuji Iwashita; Yuichi Matsubara; Kazunori Tomono; Masao Tateno; Roza Ishihara; Claudette Muller-Serieys; Shigeru Kohno
Journal: Antimicrob Agents Chemother Date: 2002-03 Impact factor: 5.191

4. In vivo efficacy of the new ketolide telithromycin (HMR 3647) in murine infection models.

Authors: A Bonnefoy; M Guitton; C Delachaume; P Le Priol; A M Girard
Journal: Antimicrob Agents Chemother Date: 2001-06 Impact factor: 5.191

5. Recovery of interfering bacteria in the nasopharynx following antimicrobial therapy of acute maxillary sinusitis with telithromycin or amoxicillin-clavulanate.

Authors: Itzhak Brook; Jeffrey N Hausfeld
Journal: Antimicrob Agents Chemother Date: 2005-11 Impact factor: 5.191

Review 6. Review of macrolides and ketolides: focus on respiratory tract infections.

Authors: G G Zhanel; M Dueck; D J Hoban; L M Vercaigne; J M Embil; A S Gin; J A Karlowsky
Journal: Drugs Date: 2001 Impact factor: 9.546

7. In vitro activities of the new ketolide HMR 3647 (telithromycin) in comparison with those of eight other antibiotics against viridans group Streptococci isolated from blood of neutropenic patients with cancer.

Authors: F Alcaide; M A Benítez; J Carratalà; F Gudiol; J Liñares; R Martín
Journal: Antimicrob Agents Chemother Date: 2001-02 Impact factor: 5.191

8. In vivo efficacy of telithromycin (HMR3647) against Streptococcus pneumoniae and Haemophilus influenzae.

Authors: H Okamoto; S Miyazaki; K Tateda; Y Ishii; K Yamaguchi
Journal: Antimicrob Agents Chemother Date: 2001-11 Impact factor: 5.191

Review 9. Telithromycin.

Authors: Keri Wellington; Stuart Noble
Journal: Drugs Date: 2004 Impact factor: 9.546

Review 10. The ketolides: a critical review.

Authors: George G Zhanel; Michael Walters; Ayman Noreddin; Lavern M Vercaigne; Aleksandra Wierzbowski; John M Embil; Alfred S Gin; Stephen Douthwaite; Daryl J Hoban
Journal: Drugs Date: 2002 Impact factor: 9.546