| Literature DB >> 9686877 |
J Dankers1, J van den Elshout, G Ahr, E Brendel, C van der Heiden.
Abstract
For use in clinical studies, a fast and sensitive assay method was developed for the determination of nifedipine in human plasma samples. The assay method is based on tandem mass spectrometry detection (HPLC-MS-MS). The effect of flow injection as well as HPLC separation on the results of the nifedipine determination were evaluated. The limit of quantification is 0.5 ng/ml and the accuracy (as determined by spiking recovery) was found to be good.Entities:
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Year: 1998 PMID： 9686877 DOI： 10.1016/s0378-4347(98)00126-1
Source DB: PubMed Journal: J Chromatogr B Biomed Sci Appl ISSN： 1387-2273