Literature DB >> 9684480

Dietary silymarin improves removal of low density lipoproteins by the perfused rat liver.

N Skottová1, V Krecman.   

Abstract

Silymarin administered to the rats concurrently with high cholesterol diet normalized the high cholesterol diet-induced retardation of disappearance of low density lipoproteins (LDL) from the medium during recirculating perfusion of livers from these rats. We suggest that the improvement of LDL removal by the liver after silymarin treatment contributes to the antihypercholesterolemic effect of silymarin.

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Year:  1998        PMID： 9684480

Source DB:  PubMed          Journal:  Acta Univ Palacki Olomuc Fac Med        ISSN： 0301-2514


  6 in total

1.  Development of a HPLC-UV assay for silybin-phosphatidylcholine complex (silybinin capsules) and its pharmacokinetic study in healthy male Chinese volunteers.

Authors:  Wei Li; Jun Gao; Hong-Zhi Zhao; Chang-Xiao Liu
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2006 Oct-Dec       Impact factor: 2.441

2.  Cardioprotective activity of silymarin in ischemia-reperfusion-induced myocardial infarction in albino rats.

Authors:  Pragada Rajeswara Rao; Routhu Kasi Viswanath
Journal:  Exp Clin Cardiol       Date:  2007

3.  The effects of milk thistle on hepatic fibrosis due to methotrexate in rat.

Authors:  Ali Reza Ghaffari; Hamid Noshad; Ali Ostadi; Morteza Ghojazadeh; Parviz Asadi
Journal:  Hepat Mon       Date:  2011-06       Impact factor: 0.660

4.  Silymarin-laden PVP-PEG polymeric composite for enhanced aqueous solubility and dissolution rate: Preparation and in vitro characterization.

Authors:  Abid Mehmood Yousaf; Usman Rashid Malik; Yasser Shahzad; Tariq Mahmood; Talib Hussain
Journal:  J Pharm Anal       Date:  2018-09-19

5.  The Effect of Silymarin Flavonolignans and Their Sulfated Conjugates on Platelet Aggregation and Blood Vessels Ex Vivo.

Authors:  Jana Pourová; Lenka Applová; Kateřina Macáková; Marie Vopršalová; Thomas Migkos; Roger Bentanachs; David Biedermann; Lucie Petrásková; Václav Tvrdý; Marcel Hrubša; Jana Karlíčková; Vladimír Křen; Kateřina Valentová; Přemysl Mladěnka
Journal:  Nutrients       Date:  2019-09-24       Impact factor: 5.717

6.  Silymarin-loaded solid nanoparticles provide excellent hepatic protection: physicochemical characterization and in vivo evaluation.

Authors:  Kwan Yeol Yang; Du Hyeong Hwang; Abid Mehmood Yousaf; Dong Wuk Kim; Young-Jun Shin; Ok-Nam Bae; Yong-Il Kim; Jong Oh Kim; Chul Soon Yong; Han-Gon Choi
Journal:  Int J Nanomedicine       Date:  2013-08-28
  6 in total

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