J K Nishimura1, B E Cook, J M Pach. 1. Department of Ophthalmology, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA.
Abstract
PURPOSE: To describe the clinical presentation and course of Whipple disease in an adult. METHODS: A 34-year-old man with phthisis bulbi in the right eye secondary to uveitis-induced neovascular glaucoma presented with severe acute posterior uveitis in the left eye. He underwent esophagogastroduodenoscopy and jejunal biopsy for evaluation of anemia. The posterior uveitis was treated with a subtenon injection of triamcinolone. RESULT: The diagnosis of Whipple disease was confirmed by polymerase chain reaction analysis of the jejunal biopsy that demonstrated Tropheryma whippelii rDNA. CONCLUSION: Although Whipple disease is typically evident with malabsorption, it can also present as uveitis without prominent gastrointestinal symptoms.
PURPOSE: To describe the clinical presentation and course of Whipple disease in an adult. METHODS: A 34-year-old man with phthisis bulbi in the right eye secondary to uveitis-induced neovascular glaucoma presented with severe acute posterior uveitis in the left eye. He underwent esophagogastroduodenoscopy and jejunal biopsy for evaluation of anemia. The posterior uveitis was treated with a subtenon injection of triamcinolone. RESULT: The diagnosis of Whipple disease was confirmed by polymerase chain reaction analysis of the jejunal biopsy that demonstrated Tropheryma whippelii rDNA. CONCLUSION: Although Whipple disease is typically evident with malabsorption, it can also present as uveitis without prominent gastrointestinal symptoms.
Authors: Waleed K Alsarhani; Muhannad I Alkhalifah; Hind M Alkatan; Afaf L Alsolami; Azza M Y Maktabi; Adel H Alsuhaibani Journal: BMC Ophthalmol Date: 2020-10-16 Impact factor: 2.209