PURPOSE: To determine the safety and efficacy of intracameral injections of unpreserved lidocaine to reduce intraocular sensation. SETTING: Carolina Eye Associates, Southern Pines, North Carolina, USA. METHODS: In this prospective study, 100 patients having phacoemulsification under topical anesthesia were randomly assigned to receive an intracameral injection of unpreserved lidocaine (0.5 cc of a 1% unpreserved solution) or balanced salt solution. RESULTS:Ninety-three patients completed the study. There were no significant between-group differences in cell density parameters or Kowa laser flare-cell meter measurements. Seventy-eight percent of lidocaine patients and 56% of controls reported no sensation (P = .048, Fisher's exact test). CONCLUSION:Intracameral injections of unpreserved lidocaine safely and effectively reduced intraocular sensation during phacoemulsification.
RCT Entities:
PURPOSE: To determine the safety and efficacy of intracameral injections of unpreserved lidocaine to reduce intraocular sensation. SETTING: Carolina Eye Associates, Southern Pines, North Carolina, USA. METHODS: In this prospective study, 100 patients having phacoemulsification under topical anesthesia were randomly assigned to receive an intracameral injection of unpreserved lidocaine (0.5 cc of a 1% unpreserved solution) or balanced salt solution. RESULTS: Ninety-three patients completed the study. There were no significant between-group differences in cell density parameters or Kowa laser flare-cell meter measurements. Seventy-eight percent of lidocainepatients and 56% of controls reported no sensation (P = .048, Fisher's exact test). CONCLUSION: Intracameral injections of unpreserved lidocaine safely and effectively reduced intraocular sensation during phacoemulsification.
Authors: A S Ioannidis; K Papageorgiou; K I Alexandraki; P Massaoutis; A J Sinha; P S Andreou Journal: Int Ophthalmol Date: 2010-01-28 Impact factor: 2.031
Authors: Mario D Toro; Dominika Nowakowska; Agnieszka Brzozowska; Michele Reibaldi; Teresio Avitabile; Claudio Bucolo; Paolo Murabito; Clara Chisari; Katarzyna Nowomiejska; Robert Rejdak Journal: Front Pharmacol Date: 2020-04-16 Impact factor: 5.810