Literature DB >> 9681311

Recurrent overdose: patient characteristics, habits, and outcomes.

D M Taylor1, P A Cameron, D Eddey.   

Abstract

OBJECTIVES: Patients who overdose repeatedly on drugs and poisons (repeaters) are of major concern. This study aimed to examine the demographics, types of drugs ingested, associated self inflicted trauma, and medium term outcome of repeaters and to compare these patients with those who overdosed on one occasion only (single presenters) during the study period.
METHODS: The study was undertaken in the emergency department of a large, provincial Australian hospital. A retrospective case note examination was made for all patients who presented, after drug overdose, during the two year study period. These patients were also followed up for a further 12 months after the study period.
RESULTS: The study identified 335 single presenters and 46 repeaters. Females formed about two thirds of each group but repeaters tended to be older (p > 0.05) and to present more frequently before midnight (p > 0.05). Significantly more repeat presentations were triaged to the low priority categories 4 or 5 (odds ratio (OR) 0.48; 95% confidence interval (CI) 0.26 to 0.90, p = 0.023) and this group required fewer admissions to the hospital (OR 1.85; 95% CI 1.16 to 2.93, p = 0.009). Repeaters tended to take single drug overdoses. There were significantly more paracetamol only overdoses (OR 0.54; 95% CI 0.32 to 0.92, p = 0.024) and neuroleptic only overdoses (OR 0.27; 95% CI 0.11 to 0.67, p = 0.005) in the repeater group. More repeaters caused self inflicted trauma during the study period (OR 0.20; 95% CI 0.06 to 0.64, p = 0.007). No repeater completed suicide during the study or the 12 month follow up periods but repeaters presented more frequently, after overdose, during follow up (OR 0.38; 95% CI 0.13 to 1.11, p = 0.078).
CONCLUSIONS: The study concludes that there are some significant differences between patients who overdose repeatedly and those who overdose on one occasion only. The study findings suggest that the medium term suicidal risk for repeaters is relatively low. However, this risk will vary and individual patients must be assessed thoroughly and managed accordingly.

Entities:  

Mesh:

Year:  1998        PMID: 9681311      PMCID: PMC1343140          DOI: 10.1136/emj.15.4.257

Source DB:  PubMed          Journal:  J Accid Emerg Med        ISSN: 1351-0622


  22 in total

1.  General hospital admission in the management of parasuicide. A randomised controlled trial.

Authors:  J Waterhouse; S Platt
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2.  Repeat self-harm: an 18-month follow-up.

Authors:  F Hassanyeh; G O'Brien; A R Holton; K Hurren; L Watt
Journal:  Acta Psychiatr Scand       Date:  1989-03       Impact factor: 6.392

3.  A survey of deliberate self-poisoning.

Authors:  J McGrath
Journal:  Med J Aust       Date:  1989-03-20       Impact factor: 7.738

4.  Repetition of parasuicide: an epidemiological and clinical study.

Authors:  N Kreitman; P Casey
Journal:  Br J Psychiatry       Date:  1988-12       Impact factor: 9.319

5.  Deliberate self-poisoning.

Authors:  R Farmer
Journal:  Br J Hosp Med       Date:  1986-12

6.  Suicide attempts in antisocial personality disorder.

Authors:  M J Garvey; F Spoden
Journal:  Compr Psychiatry       Date:  1980 Mar-Apr       Impact factor: 3.735

7.  Why do amitriptyline and dothiepin appear to be so dangerous in overdose?

Authors:  S A Montgomery; D Baldwin; M Green
Journal:  Acta Psychiatr Scand Suppl       Date:  1989

Review 8.  Substance abuse and adolescent suicidal behavior.

Authors:  F E Crumley
Journal:  JAMA       Date:  1990-06-13       Impact factor: 56.272

9.  Frequent deliberate self-harm: repetition, suicide and cost after three or more years.

Authors:  C R Rodger; A I Scott
Journal:  Scott Med J       Date:  1995-02       Impact factor: 0.729

10.  Age and self-poisoning: the epidemiology in Newcastle upon Tyne in the 1980s.

Authors:  H Wynne; D N Bateman; F Hassanyeh; M D Rawlins; K W Woodhouse
Journal:  Hum Toxicol       Date:  1987-11
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  5 in total

1.  Characteristics and trends of emergency patients with drug overdose in Osaka.

Authors:  Yoshie Kubota; Kohei Hasegawa; Hirokazu Taguchi; Tetsuhisa Kitamura; Chika Nishiyama; Taku Iwami; Tatsuya Nishiuchi; Atsushi Hiraide
Journal:  Acute Med Surg       Date:  2015-03-15

2.  Predicting ICU admissions from attempted suicide presentations at an Emergency Department in Central Queensland.

Authors:  Xaviour Walker; Joon Lee; Lidia Koval; Alana Kirkwood; Jessica Taylor; Justin Gibbs; Samantha Ng; Lynne Steele; Peter Thompson; Leo Anthony Celi
Journal:  Australas Med J       Date:  2013-11-30

3.  Deliberate self-poisoning presenting to an emergency medicine network in South-East melbourne: a descriptive study.

Authors:  Asheq Rahman; Catherine Martin; Andis Graudins; Rose Chapman
Journal:  Emerg Med Int       Date:  2014-06-12       Impact factor: 1.112

4.  A retrospective descriptive study of the characteristics of deliberate self-poisoning patients with single or repeat presentations to an Australian emergency medicine network in a one year period.

Authors:  Catherine A Martin; Rose Chapman; Asheq Rahman; Andis Graudins
Journal:  BMC Emerg Med       Date:  2014-08-23

Review 5.  Risk factors for repetition of self-harm: a systematic review of prospective hospital-based studies.

Authors:  Celine Larkin; Zelda Di Blasi; Ella Arensman
Journal:  PLoS One       Date:  2014-01-20       Impact factor: 3.240

  5 in total

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