Literature DB >> 9681224

Severe vincristine toxicity in combination with itraconazole.

J Gillies1, K A Hung, E Fitzsimons, R Soutar.   

Abstract

We report two patients with acute lymphoblastic leukaemia (ALL) who were entered into the current MRC adult ALL trial (UKALL XII) in whom unusually severe vincristine induced neurotoxicity developed. This appeared to be the result of an interaction with itraconazole suspension.

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Year:  1998        PMID： 9681224     DOI： 10.1046/j.1365-2257.1998.00103.x

Source DB:  PubMed          Journal:  Clin Lab Haematol        ISSN： 0141-9854


  6 in total

Review 1.  Adverse interactions between antifungal azoles and vincristine: review and analysis of cases.

Authors:  Brad Moriyama; Stacey A Henning; Janice Leung; Oluwaseun Falade-Nwulia; Paul Jarosinski; Scott R Penzak; Thomas J Walsh
Journal:  Mycoses       Date:  2011-11-29       Impact factor: 4.377

Review 2.  Effects of the antifungal agents on oxidative drug metabolism: clinical relevance.

Authors:  K Venkatakrishnan; L L von Moltke; D J Greenblatt
Journal:  Clin Pharmacokinet       Date:  2000-02       Impact factor: 6.447

3.  Potential drug interactions and chemotoxicity in older patients with cancer receiving chemotherapy.

Authors:  Mihaela A Popa; Kristie J Wallace; Antonella Brunello; Martine Extermann; Lodovico Balducci
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Review 4.  The enzymatic basis of drug-drug interactions with systemic triazole antifungals.

Authors:  Yasmine Nivoix; Dominique Levêque; Raoul Herbrecht; Jean-Claude Koffel; Laurence Beretz; Genevieve Ubeaud-Sequier
Journal:  Clin Pharmacokinet       Date:  2008       Impact factor: 6.447

5.  Aspects of vincristine-induced neuropathy in hematologic malignancies: a systematic review.

Authors:  Marie Lindhard Madsen; Hanne Due; Niels Ejskjær; Paw Jensen; Jakob Madsen; Karen Dybkær
Journal:  Cancer Chemother Pharmacol       Date:  2019-06-18       Impact factor: 3.333

6.  Hyponatremia During Induction Therapy in Distinct Pediatric Oncological Cohorts: A Retrospective Study.

Authors:  Christina Salvador; Robert Salvador; Peter Willeit; Christine Kuntner; Alexandra Haid; Thomas Müller; Gabriele Kropshofer; Roman Crazzolara
Journal:  Front Oncol       Date:  2021-10-29       Impact factor: 6.244
  6 in total

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