Literature DB >> 9681130

Adenosine receptors: new opportunities for future drugs.

S A Poulsen1, R J Quinn.   

Abstract

This review summarises current knowledge on adenosine receptors, an important G protein-coupled receptor. The four known adenosine receptor subtypes A1, A2A, A2B, and A3 are discussed with special reference to the opportunities for drug development.

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Year:  1998        PMID： 9681130     DOI： 10.1016/s0968-0896(98)00038-8

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  50 in total

Review 1.  A(2A) adenosine receptors in human peripheral blood cells.

Authors:  S Gessi; K Varani; S Merighi; E Ongini; P A Borea
Journal:  Br J Pharmacol       Date:  2000-01       Impact factor: 8.739

2.  Signaling by extracellular nucleotides and nucleosides.

Authors:  P Illes; K N Klotz; M J Lohse
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2000-11       Impact factor: 3.000

Review 3.  Mast cells. Receptors, secretagogues, and signaling.

Authors:  Bhavya B Sharma; John R Apgar; Fu-Tong Liu
Journal:  Clin Rev Allergy Immunol       Date:  2002-04       Impact factor: 8.667

4.  Molecular modeling the human A1 adenosine receptor and study of the mechanisms of its selective ligand binding.

Authors:  A A Ivanov; I I Baskin; V A Palyulin; N S Zefirov
Journal:  Dokl Biochem Biophys       Date:  2002 Sep-Oct       Impact factor: 0.788

5.  Molecular modeling of the human A2a adenosine receptor.

Authors:  A A Ivanov; I I Baskin; V A Palyulin; N S Zefirov
Journal:  Dokl Biochem Biophys       Date:  2003 Mar-Apr       Impact factor: 0.788

6.  Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice.

Authors:  Ilia Korboukh; Emily A Hull-Ryde; Joseph E Rittiner; Amarjit S Randhawa; Jennifer Coleman; Brendan J Fitzpatrick; Vincent Setola; William P Janzen; Stephen V Frye; Mark J Zylka; Jian Jin
Journal:  J Med Chem       Date:  2012-07-16       Impact factor: 7.446

7.  Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway.

Authors:  Mahmoud Aghaei; Mojtaba Panjehpour; Fatemeh Karami-Tehrani; Siamak Salami
Journal:  J Cancer Res Clin Oncol       Date:  2011-08-10       Impact factor: 4.553

8.  Mappability of drug-like space: towards a polypharmacologically competent map of drug-relevant compounds.

Authors:  Pavel Sidorov; Helena Gaspar; Gilles Marcou; Alexandre Varnek; Dragos Horvath
Journal:  J Comput Aided Mol Des       Date:  2015-11-12       Impact factor: 3.686

9.  9-Ethyladenine derivatives as adenosine receptor antagonists: 2- and 8-substitution results in distinct selectivities.

Authors:  Karl-Norbert Klotz; Sonja Kachler; Catia Lambertucci; Sauro Vittori; Rosaria Volpini; Gloria Cristalli
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2003-05-07       Impact factor: 3.000

10.  Synthesis and evaluation of N⁶-substituted apioadenosines as potential adenosine A₃ receptor modulators.

Authors:  Kiran S Toti; Steven M Moss; Silvia Paoletta; Zhan-Guo Gao; Kenneth A Jacobson; Serge Van Calenbergh
Journal:  Bioorg Med Chem       Date:  2014-05-23       Impact factor: 3.641
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