Prevention and treatment of diabetic foot wounds.

The diabetic foot ulcer is one of the most common and devastating complications of diabetes mellitus. These ulcers account for most of the hospital admissions for patients with diabetes, and they represent a common precursor for amputation. When a diabetic foot ulcer becomes infected, gangrene and amputation can follow in rapid succession. Recent reviews concerning diabetic foot lesions and amputations have stressed the magnitude and importance of aggressive management. This management is complicated, and typically requires radical débridement, appropriate antibiotics, non-weight-bearing, and vascular surgery when indicated. A variety of adjunctive therapy can be helpful, including hyperbaric oxygen and topical growth factors. The most important step in preventing ulceration of the foot is patient education in foot care.