Literature DB >> 9677269

Four new sesquiterpenes from Petasites formosanus.

Y L Lin1, C H Mei, S L Huang, Y H Kuo.   

Abstract

Four new eremophilane-type sesquiterpenes, petasones A (1) and B (2), S-petasitin (3), and petasinol (4), were isolated from the aerial parts of Petasites formosanus. Their structures were elucidated by spectroscopic and chemical methods as 3alpha-[(Z)-3-methylsulfinylacryloxy]eremophila-7(11), 9-dien-8-one; 3alpha-[(E)-3-methylsulfinylacryloxy]eremophila-7(11), 9-dien-8-one; 3alpha-[(Z)-3-methylthioacryloxy]-11-hydroxyeremophila -6, 9-dien-8-one; and 3alpha-[(E)-3-methylsulfinylacryloxy]-8beta-hydroxy eremophila-9, 11-diene, respectively.

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Year:  1998        PMID： 9677269     DOI： 10.1021/np970583z

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  2 in total

1.  Calcium-antagonizing activity of S-petasin, a hypotensive sesquiterpene from Petasites formosanus, on inotropic and chronotropic responses in isolated rat atria and cardiac myocytes.

Authors:  Guei-Jane Wang; Jyh-Fei Liao; Kadon K Hintz; Wen-Pin Chen; Ming-Jai Su; Yun-Lian Lin; Chuen-Chao Shi; Chieh-Fu Chen; Jun Ren
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2004-02-04       Impact factor: 3.000

2.  S-Petasin, the Main Sesquiterpene of Petasites formosanus, Inhibits Phosphodiesterase Activity and Suppresses Ovalbumin-Induced Airway Hyperresponsiveness.

Authors:  Chung-Hung Shih; Tzu-Jung Huang; Chien-Ming Chen; Yun-Lian Lin; Wun-Chang Ko
Journal:  Evid Based Complement Alternat Med       Date:  2011-02-10       Impact factor: 2.629
  2 in total

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