Literature DB >> 9676258

Experimental transmission of dermal sarcoma to the sauger Stizostedion canadense.

D L Holzschu1, G A Wooster, P R Bowser.   

Abstract

Walleye dermal sarcoma virus (WDSV) has been identified as the causative agent of a benign neoplasia of walleye Stizostedion vitreum, walleye dermal sarcoma (WDS). We conducted an experimental transmission regimen to determine if WDSV is capable of inducing dermal sarcoma in the closely related sauger S. canadense. Nearly all of young-of-the-year saugers (96%) inoculated with filtrates of spring-collected tumors developed dermal sarcomas, while all of the inoculated walleyes developed tumors. Most of the sauger tumors were limited to the skin, but invasive tumors, similar to those previously observed in experimental walleyes, were observed in some fish.

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Year:  1998        PMID: 9676258     DOI: 10.3354/dao032009

Source DB:  PubMed          Journal:  Dis Aquat Organ        ISSN: 0177-5103            Impact factor:   1.802


  3 in total

Review 1.  Comparative pathogenesis of epsilonretroviruses.

Authors:  Donald Holzschu; Lorie A Lapierre; Michael D Lairmore
Journal:  J Virol       Date:  2003-12       Impact factor: 5.103

2.  Squamous epithelial proliferation induced by walleye dermal sarcoma retrovirus cyclin in transgenic mice.

Authors:  M D Lairmore; J R Stanley; S A Weber; D L Holzschu
Journal:  Proc Natl Acad Sci U S A       Date:  2000-05-23       Impact factor: 11.205

3.  Walleye dermal sarcoma virus: molecular biology and oncogenesis.

Authors:  Joel Rovnak; Sandra L Quackenbush
Journal:  Viruses       Date:  2010-09-22       Impact factor: 5.818

  3 in total

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