| Literature DB >> 9675913 |
I N Day1, E Spanakis, D Palamand, G P Weavind, S D O'Dell.
Abstract
Microplate-array diagonal-gel electrophoresis (MADGE) was invented for molecular-genetic epidemiological studies. It combines direct compatibility with microplates, convenient polyacrylamide-gel electrophoresis and economy of time and reagents at minimal capital cost, and enables one user to run up to several-thousand gel lanes per day for the direct assay of single-base variations. Melt-MADGE adds temporal-thermal-ramp apparatus to achieve similar throughput for de novo mutation scanning.Entities:
Mesh:
Year: 1998 PMID: 9675913 DOI: 10.1016/s0167-7799(98)01217-7
Source DB: PubMed Journal: Trends Biotechnol ISSN: 0167-7799 Impact factor: 19.536