Literature DB >> 9673898

Has psoriasis its own characteristic trichogram?

A Stanimirović1, M Skerlev, T Stipić, T Beck, A Basta-Juzbasić, D Ivanković.   

Abstract

The aim of this study was to determine if there were characteristic trichogram changes in scalp psoriasis in patients without clinically evident effluvium or alopecia. A total of 45 patients (17 men and 28 women, aged from 15 to 73 years) with clinically and histologically confirmed psoriasis vulgaris with scalp involvement were included. The control group consisted of 60 volunteers (23 males and 37 females aged from 15 to 74 years) with no scalp involvement. Our results from the psoriatic group showed highly increased proportions of dysplastic hair roots. Median proportion was 50% with 95% confidence interval (CI) for median 30-60%, whereas telogen hair ratio was slightly increased-median proportion was 16% with 95% CI for median 15-20%. Within the psoriasis patients' group no statistically significant correlations were found between the proportion of dysplastic hairs and the patients' age, sex, and the intensity and duration of disease. According to the results of this study, the dysplastic hairs in scalp psoriasis are statistically significant much more frequently compared with the control group. Thus, the increased proportion of dysplastic hairs in scalp psoriasis without effluvium or alopecia might be its characteristic trichogram sign.

Entities:  

Mesh:

Substances:

Year:  1998        PMID: 9673898     DOI: 10.1016/s0923-1811(97)00082-0

Source DB:  PubMed          Journal:  J Dermatol Sci        ISSN: 0923-1811            Impact factor:   4.563


  1 in total

1.  Restricted MHC-peptide repertoire predisposes to autoimmunity.

Authors:  Nadezda N Logunova; Christophe Viret; Leonid A Pobezinsky; Sara A Miller; Dmitri B Kazansky; John P Sundberg; Alexander V Chervonsky
Journal:  J Exp Med       Date:  2005-07-04       Impact factor: 14.307

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.