Literature DB >> 9672520

Inflammatory bowel disease in African-American children living in Georgia.

S O Ogunbi1, J A Ransom, K Sullivan, B T Schoen, B D Gold.   

Abstract

We describe the clinical characteristics of inflammatory bowel disease (IBD) African-American compared with non-African-American children. We identified 172 children with IBD; forty-nine (29%) were African-American. Median symptom duration before IBD diagnosis in African-American children (6 months) was shorter than that of non-African-American children (10 months). The most frequent presenting symptom was hematochezia (ulcerative colitis) and abdominal pain (Crohn's disease) in both racial groups. The estimated incidence of Crohn's disease in African-Americans ranged from 7 per 100,000 to 12 per 100,000, whereas the observed incidence in those with ulcerative colitis was between 5 and 7 per 100,000 during the 10 years of the study. Our pilot study suggests that IBD may be more common in African-American children than previously reported. Prospective population-based studies would be useful to determine whether inheritable factors linked with ethnicity are associated with IBD.

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Mesh:

Year:  1998        PMID: 9672520     DOI: 10.1016/s0022-3476(98)70187-8

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  21 in total

Review 1.  Clinical aspects and pathophysiology of inflammatory bowel disease.

Authors:  Barbara A Hendrickson; Ranjana Gokhale; Judy H Cho
Journal:  Clin Microbiol Rev       Date:  2002-01       Impact factor: 26.132

Review 2.  Genetics of inflammatory bowel disease: current status and future directions.

Authors:  Thomas D Walters; Mark S Silverberg
Journal:  Can J Gastroenterol       Date:  2006-10       Impact factor: 3.522

Review 3.  The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease.

Authors:  Jessica F Brinkworth; Luis B Barreiro
Journal:  Curr Opin Immunol       Date:  2014-10-22       Impact factor: 7.486

4.  Racial differences in disease activity and quality of life in patients with Crohn's disease.

Authors:  Leyla J Ghazi; Alison D Lydecker; Seema A Patil; Ankur Rustgi; Raymond K Cross; Mark H Flasar
Journal:  Dig Dis Sci       Date:  2014-04-10       Impact factor: 3.199

5.  Clinical presentation and disease course of inflammatory bowel disease differs by race in a large tertiary care hospital.

Authors:  M Anthony Sofia; David T Rubin; Ningqi Hou; Joel Pekow
Journal:  Dig Dis Sci       Date:  2014-04-22       Impact factor: 3.199

6.  IBD Serology and Disease Outcomes in African Americans With Crohn's Disease.

Authors:  Madeline Bertha; Arthi Vasantharoopan; Archana Kumar; Beau B Bruce; Jarod Prince; Tatyana Hofmekler; David Okou; Pankaj Chopra; Gabriel Wang; Cary Sauer; Carol J Landers; Sunny Z Hussain; Raymond K Cross; Robert N Baldassano; Michael D Kappelman; Jeffrey Katz; Jonathan S Alexander; Barbara S Kirschner; Dedrick E Moulton; Bankole O Osuntokun; Ashish Patel; Shehzad Saeed; Jan-Michael A Klapproth; Tanvi A Dhere; Marla C Dubinsky; Dermot McGovern; Subra Kugathasan
Journal:  Inflamm Bowel Dis       Date:  2017-12-19       Impact factor: 5.325

7.  Immunopathogenesis of inflammatory bowel disease.

Authors:  Julien Matricon; Nicolas Barnich; Denis Ardid
Journal:  Self Nonself       Date:  2010-10

Review 8.  Inflammatory bowel disease: genetic and epidemiologic considerations.

Authors:  Judy H Cho
Journal:  World J Gastroenterol       Date:  2008-01-21       Impact factor: 5.742

9.  African-American inflammatory bowel disease in a Southern U.S. health center.

Authors:  Hemanth Veluswamy; Kunal Suryawala; Ankur Sheth; Shannon Wells; Erik Salvatierra; Walter Cromer; Ganta V Chaitanya; Annette Painter; Mihir Patel; Kenneth Manas; Ellenmarie Zwank; Moheb Boktor; Kondal Baig; Balaji Datti; Michael J Mathis; Alireza Minagar; Paul A Jordan; Jonathan S Alexander
Journal:  BMC Gastroenterol       Date:  2010-09-09       Impact factor: 3.067

10.  Racial differences in disease extent and severity in patients with ulcerative colitis: a retrospective cohort study.

Authors:  Mark H Flasar; Sandra Quezada; Priti Bijpuria; Raymond K Cross
Journal:  Dig Dis Sci       Date:  2008-02-14       Impact factor: 3.199

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