Literature DB >> 9671958

Gene therapy for pancreatic cancer.

S Takeda1, A Nakao, K Miyoshi, H Takagi.   

Abstract

It has been approximately 7 years since the introduction of gene therapy. Since conventional procedures such as surgery, chemotherapy, and radiotherapy have had limited therapeutic value for cancer patients, the evolution of gene therapy seems a promising alternative to many researchers and clinicians. Indeed, about half of all gene therapy treatments are administered to patients with cancer. However, there are relatively few studies of using gene therapy with pancreatic cancer. We will review the general concept of gene therapy for cancer and its accomplishments to date.

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Year:  1998        PMID: 9671958     DOI: 10.1002/(sici)1098-2388(199807/08)15:1<57::aid-ssu10>3.0.co;2-0

Source DB:  PubMed          Journal:  Semin Surg Oncol        ISSN: 1098-2388


  4 in total

1.  Negative regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5.

Authors:  Guisheng Zhou; Shi-He Liu; Kelly M Shahi; Hua Wang; Xueyan Duan; Xia Lin; Xin-Hua Feng; Min Li; William E Fisher; Francesco J Demayo; David Dawson; F Charles Brunicardi
Journal:  Mol Endocrinol       Date:  2012-06-05

2.  The hypofunctional effect of P335L single nucleotide polymorphism on SSTR5 function.

Authors:  Guisheng Zhou; Marie-Claude Gingras; Shi-He Liu; Donghui Li; Zhijun Li; Robbi L Catania; Kelly M Stehling; Min Li; Giovanni Paganelli; Richard A Gibbs; Francesco J Demayo; William E Fisher; F Charles Brunicardi
Journal:  World J Surg       Date:  2011-08       Impact factor: 3.352

3.  Cell-specific cytotoxicity of human pancreatic adenocarcinoma cells using rat insulin promoter thymidine kinase-directed gene therapy.

Authors:  Thomas A Tirone; Xaio-Ping Wang; Nancy S Templeton; Tim Lee; Liz Nguyen; William Fisher; F Charles Brunicardi
Journal:  World J Surg       Date:  2004-08-03       Impact factor: 3.352

4.  Specific gene expression and therapy for pancreatic cancer using the cytosine deaminase gene directed by the rat insulin promoter.

Authors:  Xiao-Ping Wang; Kazuyuki Yazawa; Jie Yang; Deborah Kohn; William E Fisher; F Charles Brunicardi
Journal:  J Gastrointest Surg       Date:  2004-01       Impact factor: 3.452

  4 in total

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