| Literature DB >> 967156 |
Abstract
Two temperature-sensitive mutants of Chlamydomonas reinhardii Dangeard which are defective in protein synthesis were examined. Both show breakdown of their polysomes at the restrictive temperature into monosomes which do not contain fragments of mRNA. Many of the ribosomes still contain nascent peptides able to react with puromycin. The polysome breakdown involves only cytoplasmic (80S) ribosomes and is prevented or reversed when ribosome translocation is inhibited with cyloheximide.Entities:
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Year: 1976 PMID： 967156 DOI： 10.1007/BF00267568
Source DB: PubMed Journal: Mol Gen Genet ISSN： 0026-8925