Literature DB >> 9669231

Cognitive functioning in adults with Williams syndrome.

P Howlin1, M Davies, O Udwin.   

Abstract

This paper reports the results of cognitive, linguistic, and academic assessments in a representative sample of 62 adults with Williams syndrome. The average age of the group was 26 years and their mean full scale IQ was 61. Differences between Verbal and Performance IQ, and between receptive and expressive language skills, were smaller than generally found in studies of children with this condition. However, an examination of subtest scores revealed an almost identical cognitive profile to that found in children. Skills in other areas, such as reading, spelling, arithmetic, and social adaptation remained at a low level, with functioning generally being around a 6-8-year age equivalent. The consistency of reports on intellectual abilities in both child and adult studies of individuals with Williams syndrome lends increased support to the notion of a syndrome specific pattern of cognitive, linguistic, and adaptive functioning.

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Mesh:

Year:  1998        PMID: 9669231

Source DB:  PubMed          Journal:  J Child Psychol Psychiatry        ISSN: 0021-9630            Impact factor:   8.982


  29 in total

Review 1.  Cognitive and behavioral characteristics of children with Williams syndrome: implications for intervention approaches.

Authors:  Carolyn B Mervis; Angela E John
Journal:  Am J Med Genet C Semin Med Genet       Date:  2010-05-15       Impact factor: 3.908

Review 2.  Addressing the Educational Needs of Children with Williams Syndrome: A Rather Neglected Area of Research?

Authors:  Olympia Palikara; Maria Ashworth; Jo Van Herwegen
Journal:  J Autism Dev Disord       Date:  2018-09

3.  Using novel control groups to dissect the amygdala's role in Williams syndrome.

Authors:  Tricia A Thornton-Wells; Suzanne N Avery; Jennifer Urbano Blackford
Journal:  Dev Cogn Neurosci       Date:  2011-07       Impact factor: 6.464

4.  Affiliative behavior in Williams syndrome: social perception and real-life social behavior.

Authors:  Anna Järvinen-Pasley; Ralph Adolphs; Anna Yam; Kiley J Hill; Mark Grichanik; Judy Reilly; Debra Mills; Allan L Reiss; Julie R Korenberg; Ursula Bellugi
Journal:  Neuropsychologia       Date:  2010-04-10       Impact factor: 3.139

5.  The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.

Authors:  Geert Vandeweyer; Nathalie Van der Aa; Edwin Reyniers; R Frank Kooy
Journal:  Am J Hum Genet       Date:  2012-05-17       Impact factor: 11.025

6.  Theory of mind in Williams syndrome assessed using a nonverbal task.

Authors:  Melanie A Porter; Max Coltheart; Robyn Langdon
Journal:  J Autism Dev Disord       Date:  2008-05

7.  Atypical hemispheric asymmetry in the perception of negative human vocalizations in individuals with Williams syndrome.

Authors:  Anna Järvinen-Pasley; Seth D Pollak; Anna Yam; Kiley J Hill; Mark Grichanik; Debra Mills; Allan L Reiss; Julie R Korenberg; Ursula Bellugi
Journal:  Neuropsychologia       Date:  2009-12-11       Impact factor: 3.139

8.  Intelligence in Williams Syndrome is related to STX1A, which encodes a component of the presynaptic SNARE complex.

Authors:  Michael C Gao; Ursula Bellugi; Li Dai; Debra L Mills; Eric M Sobel; Kenneth Lange; Julie R Korenberg
Journal:  PLoS One       Date:  2010-04-21       Impact factor: 3.240

Review 9.  Defining the social phenotype in Williams syndrome: a model for linking gene, the brain, and behavior.

Authors:  Anna Järvinen-Pasley; Ursula Bellugi; Judy Reilly; Debra L Mills; Albert Galaburda; Allan L Reiss; Julie R Korenberg
Journal:  Dev Psychopathol       Date:  2008

10.  Amygdala response to faces parallels social behavior in Williams syndrome.

Authors:  Brianna M Paul; Abraham Z Snyder; Frank Haist; Marcus E Raichle; Ursula Bellugi; Joan Stiles
Journal:  Soc Cogn Affect Neurosci       Date:  2009-07-24       Impact factor: 3.436

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