Literature DB >> 9667908

Catalytic antibodies.

P Wentworth1, K D Janda.   

Abstract

Following the end of the first decade in catalytic antibody research, recent efforts are reflecting a more introspective view of the field. Notably, X-ray crystal structure analyses of antibody catalysts are permitting an increased understanding of the evolution and modus operandi of these remarkable biocatalysts. Additionally, the breadth and scope of new antibody-catalyzed reactions and novel hapten design strategies have continued to flourish with support from an increasing number of contributors to this ever expanding area.

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Year:  1998        PMID: 9667908     DOI: 10.1016/s1367-5931(98)80046-x

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN: 1367-5931            Impact factor:   8.822


  2 in total

1.  Antibodies have the intrinsic capacity to destroy antigens.

Authors:  A D Wentworth; L H Jones; P Wentworth; K D Janda; R A Lerner
Journal:  Proc Natl Acad Sci U S A       Date:  2000-09-26       Impact factor: 11.205

2.  A bait and switch hapten strategy generates catalytic antibodies for phosphodiester hydrolysis.

Authors:  P Wentworth; Y Liu; A D Wentworth; P Fan; M J Foley; K D Janda
Journal:  Proc Natl Acad Sci U S A       Date:  1998-05-26       Impact factor: 11.205

  2 in total

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