| Literature DB >> 9666316 |
Abstract
The assembly of mitochondrial NADH: ubiquinone oxidoreductase (complex I) was studied in the E35 stopper mutant of Neurospora crassa at different times during growth in liquid media. Assembly of complex I as well as of its membrane domain is impaired in this strain throughout the growth period. Nevertheless, a structure that resembles the peripheral aim of the enzyme is still formed in the mitochondria of this mutant. The absence of the membrane domain of complex I in E35 can be attributed to the specific deletion of the mitochondrial ND2 and ND3 subunits of the enzyme.Entities:
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Year: 1998 PMID: 9666316
Source DB: PubMed Journal: Biochem Cell Biol ISSN: 0829-8211 Impact factor: 3.626