Determination of T1rho values for head and neck tissues at 0.1 T: a comparison to T1 and T2 relaxation times.

In order to optimize head and neck magnetic resonance (MR) imaging with the spin-lock (SL) technique, the T1rho relaxation times for normal tissues were determined. Furthermore, T1rho was compared to T1 and T2 relaxation times. Ten healthy volunteers were studied with a 0.1 T clinical MR imager. T1rho values were determined by first measuring the tissue signal intensities with different locking pulse durations (TL), and then by fitting the signal intensity values to the equation with the least-squares method. The T1rho relaxation times were shortest for the muscle and tongue, intermediate for lymphatic and parotid gland tissue and longest for fat. T1rho demonstrated statistically significant differences (p < 0.05) between all tissues, except between muscle and tongue. T1rho values measured at locking field strength (B1L) of 35 microT were close to T2 values, the only exception being fat tissue, which showed T1rho values much longer than T2 values. Determination of tissue relaxation times may be utilized to optimize image contrast, and also to achieve better tissue discrimination potential, by choosing appropriate imaging parameters for the head and neck spin-lock sequences.